pharmacology MCQs – Page 9

Practise focused pharmacology questions with marked answers for exam preparation and subject revision.

pharmacology Mcqs
401. Which of the following is caused by Amphotericin B____________?
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A. Hyperkalemia

B. Hyponatremia

C. Hypermagnesemia

D. Hypo Kalemia
402. An excess of which of the following hormones may be associated with increased sensitivity to epinephrine ?
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A. Parathyroid

B. Thyroid

C. Insulin

D. Testosterone

403. Clavulanic acid added to ampicillin causes_____________?
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A. Increase effectivity against gram-positive organisms

B. Increase the effectiveness against delta lactamase producing organism

C. Increase effectivity against gram-negative organisms

D. Inhibition of B-lactamases
404. Slufonamides mainly interferes with the bacterial______________?
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A. Translation

B. Transcription mechanisms

C. Ribosomal function

D. PABA
405. Agents/Drugs which help in rapid coagulation of Blood_______________?
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A. Haemostatics

B. Astrigents

C. All of the above

D. Styptics

406. Antifungal drug not used in the treatment of imtestinal candidiasis______________?
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A. Clotrimazole

B. Nystatin

C. Amphotericin

D. Ketoconazole

407. All of the following have receptors which are transcription factors except____________?
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A. Vitamin D

B. Estrogen

C. Glucocorticoid

D. Insulin
408. Ototoxicity and nephrotoxicity is caused by______________?
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A. antibiotic

B. Antifungal

C. Antiviral

D. Antiemetic

409. Tetracyclines act by__________________?
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A. Inhibiting peptidyl transferase

B. Inactivating elongation factors

C. Inhibiting the binding of aminoacyl tRNA to the ribosomal complex

D. Causing misreading of mRNA

410. In the treatment of intestinal of intestinal and extraintestinal amoebiasis which of the following drug is useful____________?
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A. Metronidazole

B. Cefaclor

C. Chloroquine

D. Diloxane

411. Which of the following drug does not show renal toxicity_____________?
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A. Streptomycin

B. Gentamycin

C. Methoxyprenaline

D. Isoflurane
412. Which of the following is a characteristic of tetracycline stains ?
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A. Stained teeth fluoresce light yellow under U.V light

B. Stains are dark brown in color

C. There is less deposition in dentine as compared to enamel

D. Is always accompanied by hypolastic defects

413. One of the following is not penicillinase susceptible______________?
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A. Piperacillin

B. Cloxacillin

C. Penicillin G

D. Amoxicillin

414. Role of Heparin_____________?
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A. Prevents synthesis of prothrombin

B. Prevents synthesis of fibrinogen

C. Prevents prothrombin conversion to thrombin

D. Prevents conversion of fibrinogen to fibrin

415. Which of the following drugs is not hypoglycemic?
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A. Gluengon

B. Glibenclamide

C. Tolbutamide

D. Ethosuxinide

416. The highest risk associated with use of oral contraceptives in________________?
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A. Permanent sterility

B. Thromboembolic disorders

C. Cancer of breast

D. Hepatic necrosis

417. Which of the following receptors is activated by acetylcholine and blocked by atropine______________?
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A. Nicotinic

B. Beta 1 and 2

C. Alpha 1 and 2

D. Muscarinic
418. All except one are centrally acting muscle blocks___________?
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A. Diazepam

B. Dantrolene sodium

C. Meprobamate

D. Baclofen

419. Which among the drugs given below, does Not act by protease inhibition ?
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A. Saquinavir

B. Ritonavir

C. Zanamivir

D. Nelfinavir

420. The drug of choice for treatment of tyhoid is____________?
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A. Metronidazole

B. Ciprofloxacin

C. Tetracycline

D. Cefotaxim

421. All of the following drugs are components of the MOPP cancer Chemotherapy regimen EXCEPT______________?
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A. Procarbazine

B. Methotrexate

C. Vincristine

D. Mechlorethamine

422. Oral contraceptive failure occurs in a patient on Rifampicin because of____________?
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A. Rifampicin induce the metabolism of contra ceptive

B. Rifampicin antagonize the action of oral contraceptive

C. Rifampicin simulates gonadotropin relase from pituitary

D. Rifampicin decrease the secretion of progestin

423. The bacterial resistance to tetracycline is due to___________?
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A. Decreased uptake of drug by bacteria

B. Alteration of dehydrofolate reductase

C. Inactivation of drug by enzymes

D. Alteration of drug binding sites

424. Which of the following drugs in likely to damage the eighth cranial nerve when administered for a long period of time ?
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A. Streptomycin

B. Ethambutol

C. Isoniazid

D. Rifampicin

425. Morphine withdrawal is characterized by all EXCEPT_____________?
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A. Yawning

B. Diarrhoea

C. Lacrimation

D. Miosis
426. First line of antitubercular drug is_____________?
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A. Ethambutol

B. INH

C. Streptomycin

D. Cephalosporins

427. All of the following are features of streptomycin drug except______________?
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A. It is an antitubercular drug

B. Effective against g-ve organisms

C. It can be given orally

D. None of the above

428. Agent used in oral thrush_____________?
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A. Miconazole

B. Amoxycillin

C. Clobetasol

D. Clotrimazole
429. Scopolamine helps in________________?
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A. A & C

B. Decreased secretions

C. Motion sickness

D. Hypertension

430. Which of the following is not a broad spectrum antibiotic ?
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A. Tetracycline

B. Chloramphenicol

C. Cephalosporins

D. Doxycyclin

431. Morphine is a_____________?
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A. Sedative

B. Alkaloid

C. Diuretic

D. Anti hypertensive

E. Both A & B
432. Excessive bleeding due to heparin overdose is controlled by______________?
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A. Factor VIII

B. Vitamin K

C. Protamine sultate

D. EADA

433. Which of the following antihypertensive agents in most likely to cause an exaggerated response to an injected catecholamine_____________?
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A. Hydralazine

B. Gauanethidine

C. A thiazide diuretic

D. Propranolol

434. Mechanism of action of chlortetracycline_____________?
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A. Interfere with metabolism

B. Interfere with DNA function

C. Inhibition of cell wall formation

D. Inhibition of protein synthesis
435. The most preferred acute emetic for emesis induced by anticancer drugs is______________?
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A. Metaclopromide

B. Ondensetron

C. Chlorpromazine

D. Dicyclomine

436. The drug which gives orange colour to the urine is______________?
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A. Rifampicin

B. INH

C. Streptomycin

D. Ethambutol

437. Which of the following cardiac depressants is contraindicated in a patient with cardiac arrhythmia____________?
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A. Phenytoin

B. Quinidine

C. Propranolol

D. Lidocaine

438. True about amoxycillin in comparison to ampicillin is_______________?
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A. Lower oral biovailability

B. Can be given Parenterally

C. Higher oral biovailability

D. Equal oral biovailability

439. One of the below mentioned penicillin is NOT given orally______________?
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A. Cloxacillin

B. Amoxicillin

C. Phenoxymethy penicillin

D. Carbenicillin
440. The administration of penicillin G along with probenicid result in_____________?
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A. Increased metabolis of penciling G

B. Decreased renal excretion of penciling G

C. Increased excretion of probenacid in the feaces and perspiration

D. Increased excretion of probenacid in urine

441. All of the following drugs are useful in treatment of hypertension except______________?
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A. Thiazole diuretics

B. Methyldopa

C. Reserpine

D. Ephedrine
442. Sialogouges are______________?
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A. Decrease salivary secreations

B. Indicator dye for sialography

C. Increases salivary secretions

D. Medication for over function

443. Cyclosporin is used an______________?
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A. Antiarrythmic

B. Anticancer drug

C. Immunosuppresant

D. Antibiotic

444. Hypokalemia is seen in therapy with____________?
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A. Ibuprufen

B. Corticosteroids

C. Digitalis

D. Diazepam

445. An aminoglycoside that is often combined with polymyxin and bacitracin for the treatment of topical infection is____________?
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A. Tetracycline

B. Gentamycin

C. Neomycin

D. Aztreonam

446. Not true about piperacilline is_______________?
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A. It is a ureido penicillin

B. Given parenterally

C. Inhibits Beta-lactamase

D. Active against pseudomonas aeruginose

447. The principle therapeutic action of the glucocorticoid is________________?
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A. Antianabolic

B. Antidiuretic

C. Anti-inflammatory

D. Anti-infective

448. Quindine is used to treat______________?
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A. Congestive heart failure

B. Angina pectoris

C. Hypertension

D. Atrial fibrillation
449. Redman syndrome is side effect of______________?
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A. Chloramphenicol

B. Rifampicin

C. Vancomycin

D. Tetracycline

450. Tetracycline when given to pregnant woman can cause_______________?
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A. Acute hepatic necrosis

B. Increased intracranial pressure in infant

C. Discoloration/ staining of hard structures of foetus

D. All of the above