pharmacology MCQs – Page 10

Practise focused pharmacology questions with marked answers for exam preparation and subject revision.

pharmacology Mcqs
451. All of the following statement about antimalarial drugs are correct except_____________?
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A. Primaquine is liable to cause hemolysis in patients with G6PD deficiency

B. Primaquine eliminates P. vivax and P. ovale

C. Halofantrine prolongs QT interval and causes dysarrythmia

D. Mefloquine may safely be given to air pilots
452. All of the following are therapeutic uses of penicillin G, except_____________?
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A. Rickettsial infection

B. Syphilis

C. Bacterial meningitis

D. Anthrax

453. The toxic effect of Beta receptor antagonists includes all the following EXCEPT____________?
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A. Precipitate migrainic effect

B. Worsening of preexisting asthma

C. Hypoglycemic episodes in diabetes

D. Ischemic cardiac episode on abrupt discontinuation

454. Which anti tubercullar drug will cause transjent memory loss ?
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A. Enthionamide

B. Pyrazinamide

C. Ethambutol

D. INH
455. various insulin preparations useful in the treatment of diabetes mellitus differ primarily in______________?
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A. Focus of action

B. Mode of biotransformation

C. Onset and duration of action

D. None of the above

456. Which among the following anti-HIV drugs is also used to treat viral hepatitis B ?
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A. Efavirenz

B. Ritonavir

C. Enfuvirtide

D. Lamivudine
457. Identify the drugs useful against pseudomonanas infection______________?
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A. Ceftazidine

B. Ticarcillin

C. All of the above

D. Amoxycillin

458. Triflusal is a___________________?
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A. Antibiotic

B. Anti-arthritic drug

C. Anti-inflaqmmatory drug

D. Antiplatelet drug
459. Metronidazole______________?
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A. Is active against gram-positive aerobes

B. Is mainly concentrated in saliva

C. Has no side-effects

D. Is used in management of ANUG
460. Which of the following group of drugs are a neuromuscular blocking agents_______________?
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A. Pancuronium, rocuronium

B. Pirenzipine, propanolol and propantheline

C. choline, adrenaline and amphetamine

D. Glycinium neostigamine and physostigamine

461. More potent and non toxic drug against herpes virus is_____________?
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A. Acyclovir

B. Zidovodine

C. Amontidine

D. Nystatin

462. Combination chemotherapy is used in tuberculosis in order to reduce____________?
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A. Cost of therapy

B. Dosage of drugs

C. Development of drug resistance

D. Side effects of drugs

463. All of the following are true about tolbutamide except____________?
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A. It is used in type-I diabetes mellitus

B. It acts on pancreas to stimulate release of insulin

C. It is taken orally

D. It causes alcohol intolerance

464. Which of the following antibiotics is effective in treating oral candidiasis ?
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A. Tetracycline

B. Nystatin

C. Penicillin

D. Bacitracin

465. A potent non-texic anti-herpes drug is_______________?
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A. Acyclovir

B. Ara-amp

C. Idoxyuridine

D. Vidarabine

466. Prolonged administration of streptomycin may result in damage to the____________?
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A. Facial nerve

B. Trigeminal nerve

C. Optic nerve

D. Auditory nerve
467. The most serious side effect of drug chloramp henicol is______________?
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A. Bone marrow depression

B. Angioneurotic oedema

C. Photosensitivity

D. Candidiasis

468. Which of the following is not uridopenicillin ?
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A. Mezlocillin

B. Azlocillin

C. Flucloxacillin

D. Piperacillin

469. 1st generation cephalosporin is________________?
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A. Cefepime

B. Cephadroxil

C. Cefoperazone

D. Cefotaxime

470. Which one of the following antibiotics chelates with calcium ?
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A. pencillin

B. Tetracycline

C. Cephalosporins

D. Erythromycin

471. The drug which is contraindicated in haemophilla is_________________?
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A. Dipheny 1 hydantoin

B. Penicillinium

C. Amino epsilon caproic acid

D. Aspirin
472. The incidence of allergy to penicillin among various population ranges from______________?
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A. 10% to 20%

B. 30% to 40%

C. 1% to 10%

D. 20% to 30

473. Cell wall synthesis is inhibited by all except____________?
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A. Cephalexin

B. Penicillin

C. Ampicillin

D. Lincomycin
474. When broad spectrum antibiotics are administered with coumarin anticoagulants, the anticoagulant action may be____________?
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A. Reduced because of increased protein binding

B. Reduced because of enhanced hepatic drug metabolism

C. Increase because of decrease renal excretion of the anticoagulant

D. Increased because of reduction of vitamin sources
475. All of the following are topically used sulphonamides except____________?
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A. Suphacetamide

B. Silversulphadiazine

C. Mafenide

D. Sulphadiazine
476. If patient is given Noradrenaline what will happen_______________?
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A. Cause decrease in cardiac output and relax bradycardia

B. Cause increase in B.P, due to its action on Beta receptors only

C. None of the above

D. Cause decrease in B.P, due to its action on Alpha receptors only

477. The mechanism of action of sodium nitroprusside is_____________?
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A. Block the sympathetic flow at hypothalamus

B. Direct Vasodilator

C. Increases cAMP

D. Calcium channel blocker

478. Erythromycin is_______________?
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A. All of these

B. Cidal in action

C. Static in action

D. Cidal in high concentration
479. Metronidazole is a type of___________?
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A. Quinolone

B. Antidepressant

C. Broad spectrum antibiotic

D. Imidazole derivative
480. Which of the following is NOT an important/frequent/well-known manifestation of an adverse drug reaction ?
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A. Leukaemia

B. Agranulocytosis

C. Aaemolysis

D. Aplastic anaemia

481. Which of the following combination of iron can be given both IM and IV____________?
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A. ferrous Sulphate

B. Iron Sorbitol Citrate Solution

C. Iron dextran

D. ferrous Humourate

482. The potent anti arrhythmic drug which has little negative ionotropic effect valuable in patients with poor left ventricular function_____________?
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A. Digoxin

B. Bidoprolo

C. Amiodarnone

D. Amlodipine

483. The aminoglycoside with least toxic effect is_____________?
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A. Isoniazid

B. Ethambutol

C. Streptomycin

D. Kanamycin

484. Which one of the following drugs is an antipseudomonal penicillin ?
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A. Dictoxacillin

B. Cephalexin

C. Piperacillin

D. Cloxacillin

485. The oropharyngeal and oesophageal candidiasis following long-term therapy with a broad spectrum antibiotic can be best treated with____________?
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A. Amphotericin

B. Sulfonates

C. Fluconazole

D. Griseofulvin

486. Succinylcholine is a/an______________?
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A. Short-acting narcotic

B. Non-depolarizing muscle relaxant

C. Intravenous anaesthetic agent

D. None of the above
487. Which one of the following agents/ drugs is of no value in the post operative care of the hemophiliac patient ?
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A. Factor VIII cryoprecipitate

B. Aminocarproic Acid

C. Tranexamic acid

D. Clopidogrel
488. Which of the following is a vosoconstrictor______________?
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A. Bupivacaine

B. Procaine

C. None of the above

D. Lidocaine

489. A diabetic patient developed cellulitis due to Staphylococcus aureus, Which was found to be Methicillin resistant on the antibiotic sensitivity testing. All the following antibiotics will be appropriate except_____________?
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A. Linezolid

B. Teichoplanin

C. Imipenem

D. Vancomycin

490. Among the drugs given below, which is LEAST likely to be implicated in drug induced hepatitis ?
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A. Streptomycin

B. Isoniazid

C. Ripampicin

D. Pyrazinamide

491. All of the following drugs are contraindicated in patients with G-6-PD deficiency, except____________?
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A. Nalidixic acid

B. Furazolidone

C. Ceftriaxone

D. Cotrimoxazole

492. The following are the indications for Metronidazole except_____________?
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A. Amoebiasis

B. Trichomonas infection

C. Streptococcal sore throat

D. Ulcerative gingivitis

493. Ketoconazole______________?
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A. Antibacterial

B. Chemotherapic agent

C. Antifungal agent

D. Antiviral agent

494. Steroids________________?
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A. Indicated in oral thrush

B. Can be safely given to immunocompromised patients

C. Exacerbate the inflammatory response

D. Steroids reduce the rate of repair of tissues thus delays the healing
495. Drug of choice in Amoebic liver abscess besides metronidazole is_____________?
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A. Mebendazole

B. Bephenium Naphthoate

C. Ciprofloxacin

D. Chloroquin
496. D-tubocurarine blocks the neuromuscular transmission by___________?
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A. Inactivate acetylcholine esterase enzyme

B. Blocking acetylcholine receptors

C. Destroys acetyl choline

D. Prevent release of acetyl choline

497. Mechanism of action of quinolones is______________?
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A. Inhibits DNA gyrase

B. Inhibits Bacterial protein synthesis

C. Inhibits intake of folic acid

D. Inhibits bacterial cell wall synthesis

498. Which drug causes photosensitivity______________?
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A. Cephalosporin

B. Tetracycline

C. Aminoglycoside

D. Penicillin

499. Peripheral neuritis is a complication of_______________?
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A. Pirazinamide

B. Ethambutol

C. Isoniazid

D. Rifampicin

500. Ivermectin is indicated in_____________?
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A. Intestinal nematode infection

B. All of the above

C. Scabies

D. Filariasis