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pharmacology MCQs

Practise focused pharmacology questions with marked answers for exam preparation and subject revision.

pharmacology Mcqs
1. Antagonist of morphine is_______________?
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A. Nalpuphine

B. Methadine

C. Naloxone

D. Nalosphine

2. All are true of diazapenes except____________?
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A. Benzodiazepam is used in treatment of status epilepticus

B. Benzodiazepam is used in the long term treatment of psychic disorders

C. None of the above

D. Clonazeppam is used in the treatment of petitmal epilepsy

3. Folic acid deficiency occurs in______________?
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A. Cyclosporine

B. Chloromphenicol

C. Aspirin

D. Phenytoin
4. Shortest acting opioid analgesic is______________?
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A. Sufentanil

B. Fentanyl

C. Morphine

D. Remifentanil
5. Which one of the following is NOT an ergot alkaloids_____________?
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A. Ketanserin

B. Lysergic acid diethylamide (LSD)

C. Bromocriptine

D. Methysergide

6. All of the following statements about opioids is correct except_____________?
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A. Pentazocine and buprinorphine

B. Pentazocine shows withdrawal symptoms in opioid dependent patients

C. Partial agonists are free from classic opioid adverse effects

D. Ethomorphine is similar to pethidine chemically

7. True about use of midazolam over diazepam is sedation in all except ?
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A. More potent than diazepam

B. Binds to benzodiazepine receptors with 3-4 time more avidly

C. Less thrombophlebitis due to low solubility in blond

D. More plasma binding and less toxicity

8. Quinine is obtained from CINCHONA________________?
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A. Bark

B. Leaves

C. Seed capsule

D. Root

9. The muscle relaxant effect of succinylcholine lasts for______________?
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A. 2 min

B. 10 min

C. 3-5 min

D. 1 min

10. Which among the following Not a pharmacological action of opioids______________?
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A. Miosis

B. Anti-emesis

C. Truncal rigidity

D. Cough suppression

11. Best and most effective drug to control convulsions in toxicity cases is______________?
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A. Carbemezipine

B. Phenytoin

C. Diazepam

D. Phenobarbitone

12. Ibuprofen is contraindicated in_______________?
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A. Patient having bronchitis

B. patients having fever

C. patients having asthma

D. patients having amoebic dysentery

13. The most prominent toxic effect associated with acetominophen use is______________?
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A. Haemorrhage

B. Gastric Ulceration

C. Respiratory alkalosis

D. Hepatic necrosis
14. An anxiolytic, not interacting with GABA ergic system and used in generalized anxiety is______________?
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A. Alprazolam

B. Phenobarbital

C. Diazepam

D. Buspiron
15. Which of the following drugs causes extra pyramidal symptoms_____________?
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A. Salicylates

B. Antibiotics

C. Barbiturates

D. Phenothiazines
16. Which one of the following NSAIDs has adverse effects on liver ?
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A. Ibuprofen

B. Aspirin

C. Diclofenac Sodium

D. Acetaminophen
17. All NSAIDs block cycloxygenase and____________?
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A. Prostaglandin synthesis

B. Costaglandin synthesis

C. Preglandin synthesis

D. Ectoglandin synthesis

18. Which among the following may be used as a sedatives hypnotic ?
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A. Zalcitabine

B. Zolpiden

C. Zileuton

D. Zolmitriptan

19. Following analgesic combination should be avoided ?
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A. Ibuprofen and Paracetamol

B. Ibuprofen and DIclofenac

C. Aspirin and Codeine

D. Paracetamol and Dextropropoxyphene

20. Aspirin is contraindicated in______________?
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A. Peptic ulcer

B. Hemorrhage

C. All of the above

D. Person suffering form chicken pox or small pox

21. A patient with grand mal epilepsy would likely be under treatment with_____________?
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A. Pentobarbital

B. Meprobamate

C. Trimethadione

D. Phenytoin
22. Neusea and vomiting that are associated with administration of opioid analgesic is the result of stimulation of the_____________?
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A. Limbic system

B. Emetic system

C. Chemoreceptor trigger zone (CTZ)

D. Opioid receptors in G.I.T

23. Clotting time is most like to be prolonged by the administration of____________?
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A. Barbiturates

B. Acetominophen

C. Acetyl salicylic acid

D. Vitamin K

24. The Ethyl alcohol (Ethanol) is more effective when mixed with water and used as_____________?
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A. 60 to 70 percent

B. 40 to 50 percent

C. 20 to 30 percent

D. 10 to 20 percent

25. Which of the following drugs is currently widely used in treating opioid dependent individuals?
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A. codeine

B. Alphaprodine

C. Pentazocine

D. Methadone
26. Narcotic overdose can be antagonized by______________?
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A. Naloxane

B. Diphenhydramine

C. Nalorphine

D. Atropine

27. Thiopentone action is terminated by______________?
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A. Excretion

B. Redistribution

C. Metabolism

D. Recycling

28. Birbiturates in pediatrics is_____________?
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A. Not much use

B. Low safety

C. Can be used safely

D. Contraindicated

29. Amitryptyline is a____________?
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A. Antibiotic

B. Sedative

C. Tricyclic antidepressant

D. Diuretic

30. Thyroid storm can be treated by all the following drugs EXCEPT______________?
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A. Dexamethasone

B. Aspirin

C. Propylthiouracil

D. Propranolol

31. Verrils sign is seen in_________________?
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A. Digitalis toxicity

B. Diazepam administration

C. Pagets disease

D. Unconscious states

32. The rate of injection of intravenous Valium is_______________?
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A. 1 mg / min

B. 2.5 ml / min

C. 1 ml / min

D. 2.5 mg / min

33. A common side effect associated with all NSAID drugs is_______________?
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A. Drowsiness

B. Constipation

C. Gastric irritation

D. Xerostomia

34. Aspirin is avoided in children with influenza infection because of association______________?
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A. Acid-base imbalance

B. Diarrhoea

C. Reyes syndrome

D. Nausea

35. BEnzodiazepines are true in___________________?
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A. All have metabolically active substrates

B. After metabolism of other drugs in liver

C. Produce distortion in sleep more than other sedatives

D. More safe than other sedatives when take in larger amounts
36. Aspirin produces all of the following effects except_____________?
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A. Frank gastric bleeding

B. Prolonged prothrombin time

C. Platelet dysfunction

D. Constipation
37. An attack of bronchial asthma is most likely to be triggered by________________?
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A. Aspirin

B. Ibuprufen

C. Diclofenac potassium

D. Mefenamic acid

E. Both A & B
38. Aspirine cause_____________?
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A. Increase APTT

B. Increase PTT

C. Increase CT

D. Increase BT
39. Which among the following is a pure antagonist of opioid receptors ?
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A. Natrexone

B. Pentazonice

C. Nalbuphine

D. Butorphanol

40. Which of the following is a muscle relaxant_________________?
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A. Pentazocine

B. Phenylephrine

C. Hyoscin

D. Scoline

41. Gastric irritation is minimum with one of the following non-steroidal anti inflammatory drugs_____________?
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A. Tenoxicam

B. Piroxicam

C. Indomethacin

D. Meloxicam
42. Which of the following is a short acting barbiturate ?
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A. Phenobarbita

B. Secobarbital

C. Diazepam

D. Pentobarbital

43. Paracetamol is contraindicated in_______________?
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A. Chronic hepatitis

B. Bleeding disorders

C. Nephritis

D. A & B
44. A Hemophiliac patient has rheumatold arthritis. Which drug might be prescribed to relieve the pain ?
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A. Phenylbutazone

B. Acetaminophen

C. Acetylsalicylic acid

D. Naproxen

45. Prolonged use of aspirin leads to______________?
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A. Bleeding defects

B. peptic ulcer

C. Carcinoma

D. A & B
46. Which of the following opioids is not given intrathecally ?
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A. Sufentanil

B. Fentanyl

C. Remifentanil

D. Morphine

47. Aspirin causes___________?
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A. Aplastic anemia

B. Hypoprothrombinemia

C. Agranulocytosis

D. Hemolytic anemia

48. Aspirin is used in treatment of Myocardial Infarction___________?
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A. It stimulates Prostacyclins

B. It is a vasodilator

C. It inhibits thromboxanes

D. Ithelps in reducing inflammatory aggregate

49. Activation of which of the following receptors would be expected to decrease anxiety_____________?
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A. Nicotinic cholinergic receptors

B. Glutamate receptors

C. Glucocorticoid receptors

D. GABA receptors
50. Which of the following drugs can be given safely to a patient with renal disease ?
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A. Aminoglycoside

B. Diazepam

C. Phenacetin

D. Tetracycline