pharmacology Mcqs
501. Chloramphenicol can cause_____________?
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A. Staining of teeth

B. B & C

C. Bone marrow suppression

D. Aplastic anaemia

504. Tetracycline chelates with______________?
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A. Mg salts

B. All of the above

C. Ca salts

D. All salts

505. Cephalosporin active against pseudomonas aeruginosa______________?
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A. Cefotaxime

B. Ceftriaxone

C. Cefoperazone

D. Cefaclor

506. Phototoxicity is the side effect of_____________?
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A. Erythormycin

B. Penicillin

C. Streptomycin

D. Demeclocycline
507. Bleeding from the oral mucosa can be reduced by topical use of_______________?
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A. Hydrocortisone

B. Dicoumarol

C. Epinephrine

D. Lidnocaine

508. Clavulanic acid is given in combination with amoxicillin in order to____________?
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A. Prolong amoxicillins half-life

B. Reduce the risk allergic reactions:

C. Extend amoxicillins antibacterial spectrum

D. Reduce the severity of diarrhea

510. Which is NOT a 2nd generation antihistaminic ?
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A. Cyclizine

B. Loratidine

C. Terfenidine

D. Acrivastatine

511. Drugs which cause ototoxicity and circumoral paraesthesia are______________?
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A. Antileprotic drugs

B. Streptomycin

C. Chloramphenicol

D. Antitubercular drugs

512. Which of the following is third generation cephalosporin ?
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A. Cefoxitin

B. Cefadroxil

C. Cefuroxime

D. Cefeperazone
514. Which of the following penicillins can be given by IV route ?
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A. Benzathine

B. Crystalline

C. Benzathamine

D. Procaine

515. Jerisch-Heximer reaction is treated by administering______________?
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A. Steroids

B. Intravenous Penicillin G

C. Antihistamines

D. Tetracyclines

516. A patient is having bronchodilation, increased temperature, constipation and tachycardia. The tentative diagnosis is_______________?
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A. Mushroom poisoning

B. Paracetamol poisoning

C. Atropine poisoning

D. Oraganophosphate poisoning

517. Antibiotic that interferes with DNA function is_____________?
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A. Tetracycline

B. Metronidazole

C. Sulphonamides

D. Nystatin

518. One of the drug is betalactamase inhibitor_____________?
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A. Ampicillin

B. Cloxacillin

C. Sulbactum

D. Pencillin G

519. Cross resistance of isoniazid is seen with_____________?
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A. Ethionamide

B. Rifampicin

C. Ethambutol

D. Cycloserine

520. Warfarin therapy is prolonged by all except______________?
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A. Erythromycin

B. Rifampicin

C. Tetracycline

D. Amoxycillin

521. Atropine is used in______________?
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A. Organophosphate poisoning

B. Trigeminal neuralgia

C. Syncope

D. Chronic glaucoma

522. Beta 2 agonist causes_______________?
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A. Vasoconstriction

B. Mydriasis

C. Bronchial muscle relaxation

D. Contraction of urinary spinctors

523. Nevirapine is a______________?
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A. Fusion inhibitor

B. Protease inhibitor

C. Non-nucleoside reverse transcriptase inhibitor

D. Nucleoside reverse transcriptase inhibitor

524. The metabolic effects of sympathomimetics are mediated by__________________?
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A. Beta 2 receptors

B. Opioid receptors

C. All beta-adrenergic receptors

D. Dopaminergic receptors

525. Isosorbide 5 mononitrate is preferred because____________?
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A. Direct coronary vasodilatory action is more

B. Sublingual absorption is better

C. Less tolerance develops

D. Longer duration of action
527. Which of the following is not an action of epinephrine when administered intravenously in a high dose ?
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A. Increased liver glycogenolysis

B. Evokes extrasystoles in the heart

C. Produces restlessness and anxiety

D. Causes broachiolar constriction
528. Which of the following synthetic sterioid shows predominantly mineralocorticoid action ?
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A. Fludrocortisone

B. Hydrocortisone

C. Dexamethsone

D. Spironolactone

529. Which of the following drug control lepramin reaction____________?
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A. Clofazimine

B. Dapsone

C. Streptomycin

D. Ethambutol

530. All of the following drugs are non depolarizing neuromuscular blocking agents except_______________?
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A. Succinylcholine

B. Gallamine triethiodide

C. D-tubocurarine

D. Pancuronium bromide

531. An oral hypoglycemic agent is______________?
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A. Warfarin

B. Insultin

C. Gluengon

D. Glibeneclamide
534. Which of the following drugs undergoes Hoffmann elimination ?
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A. d-tubecurarine

B. Acetazolamide

C. Atracurium

D. Acetycholine

535. Drugs producing ototoxicity and Nephro toxicity are______________?
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A. Macrolides

B. Tetracyclines

C. Quinalones

D. Aminoglycosides
536. Granesetron, the antiemetic properties because of____________?
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A. Gaba-inhibitory actions

B. Dopaminergic receptor blocking actions

C. Gabamimetic actions

D. Serotonin receptor blocking action
539. Which antibiotic is effective against pseudomonas and indole +ve proteus ?
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A. Oxacillin

B. Lincomycin

C. Methicillin

D. Carbenicillin
540. In treating Xerostomia, Which of the following might be prescribed ?
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A. Atropine

B. Scopalamine

C. Neostigmine

D. Ephedrine

541. Identify the factors which decrease the effect of Oral anticoagulants_______________?
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A. Pregnancy

B. Nephrotic syndorme

C. Newborn

D. Liver disease

E. Both A & B
542. Drugs causing hyperglycemia_______________?
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A. Glucocorticoids

B. a-blockers

C. Acetylcholine

D. B-blocker

543. Dry mouth during antidepressant therapy is caused by blockade of______________?
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A. Dopaminergic receptors

B. Serotonergic receptors

C. Muscarinic acetylcholine receptors

D. GABA receptors

545. Desfuroxamide is a drug used for____________?
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A. Kala azar

B. Pernicious anaemia

C. Pain control

D. Thalassemia
546. The drug which is used to treat laryngospasm is_______________?
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A. Atropine

B. Neostigmine

C. Diazepam

D. Succinylcholine
547. Mode of action of sulphonyl ureas includes all the following except______________?
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A. Decreasing Glucose absorption from the qut

B. Inhibiting gluconeogenesis in liver

C. Activating receptors on beta cells of pancreas to release insulin

D. Enhancing insulin mediated post receptor enzyme reaction

548. Oral infection by penicillinase producing organisms should be treated with____________?
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A. Ampicillin

B. Dicloxacillin

C. Erythromycin

D. Any of the above

549. The antibiotic of choice in patients sensitive to penicillin is___________?
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A. Tetracycline

B. Chloramphenicol

C. Erythromycin

D. Streptomycin

550. Tetracycline in children causes____________?
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A. Peg teeth

B. Calcification

C. Discolored teeth

D. Missing teeth