9053. Km value indicates______________?
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A. Affinity

B. Purity of Enzyme

C. Physiological role

D. Half life enzymes drug complex
9054. Which of the following statements regarding nitroglycerin is true ?
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A. Poorly suited for oral administration

B. High membrane penetrability

C. All of the above

D. The effect is more pronounced in venous

9055. About heparin true is_____________?
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A. Decrease action of prothrombin III

B. Half-life is 90 min

C. Known to cause idiopathic thrombocytosis

D. Mixture of sulphated polypeptide

9057. Mandibular sublaxation is associated with________________?
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A. Ciprofloxacin

B. Prochlorperazine

C. Diphenhydramine

D. Carbamezapine

9058. Gastric secretion has been shown to be most effectively reduced with the use of___________?
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A. Adrenal steroids

B. H1 histamine receptor antagonist

C. Anticholinergic

D. H2 histamine receptor antagonist
9060. When a drug creates an effect that is unpredictable and unique it is termed as____________?
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A. Idiosyncratic effect

B. Toxicity effect

C. Drug on Drug effect

D. Side effect

9061. Nitrous oxide is carried in the blood stream by_____________?
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A. Red Blood cells

B. White blood cells

C. Serum

D. Haemoglobin

9062. Drugs showing zero order kinetics of elimination_____________?
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A. Are more common than first order kinetics

B. Show a plot of drug concentration versus time that is linear

C. Have a half life independent of dose

D. Decrease in concentration exponentially with time

9063. Rapid onset of inhalational GA depends on____________?
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A. All of the above

B. Cerebral blood flow

C. Partial pressure of GA

D. Blood solubility

9064. Loading dose depends on_____________?
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A. Volume of distribution

B. Half life

C. Clearance

D. Rate of administration

9065. All of the following are tocolytic except_______________?
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A. Atosiban

B. Ritodrine

C. Natrexam

D. Isoxsuprine

9066. Which of the following is not a contraindication in the therapy with opioids_____________?
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A. Use in severe constant pain

B. Use in head injury patient

C. Use of agonist with mixed agonist-antagonist

D. use in impaired pulmonary function

9067. Drug injury may be caused by therapeutic drugs or______________?
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A. Carcinogens

B. Nontherapeutic agents

C. All of the above

D. Allergens

9068. American society of anesthesiologists physical status classification system, P2 is a is a patient who______________?
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A. Is healthy

B. With mild systemic disease

C. None of the above

D. With severe systemic disease

9070. Pregnant patient can be safely given______________?
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A. Barbiturates

B. Paracetamol

C. Metronidazole

D. Tetracycline

9072. Not true about penicillin G is______________?
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A. More concentrated in prostatic secretions and intraocular fluids

B. Very active against sensitive gram positive cocci

C. Destroyed by gastric acid

D. Used for treatment of meningococcal meningitis

9073. NSAID which undergoes enterohepatic circulation______________?
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A. Phenylbutazone

B. Piroxicam

C. Ibuprofen

D. Aspirin

9075. Bronchospasm can be precipitated by______________?
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A. Salbutamol

B. propranolol

C. Atropine

D. Adrenaline

9077. Which of the following is a leukotriene antagonist ?
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A. Misopristol

B. Nedocromil

C. Zileuton

D. Montelukast
9079. Lidocaine produces its antiarrhythmic effects by_____________?
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A. Increasing A-V conduction

B. Increasing cardiac conduction velocity

C. Increasing spontaneous pacemaker activity

D. Decreasing cardiac excitability
9080. Finasteride is a ?
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A. PDE inhibitor

B. Androgen receptor blocker

C. Alpha blocker

D. 5 alpha reductase inhibitor
9081. Potassium permanganate is used for_______________?
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A. Cleaning surgical instruments

B. Dinisfect water in wells

C. Irrigating cavities

D. Gargling

9082. Drugs used in cysticercosis_______________?
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A. Niclosamide

B. Pyrantel

C. Metronidazole

D. Prazequantal
9083. Aspirin acts on which part of brain ?
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A. Substantia gelatinosa

B. Medulla

C. Cortex

D. Limbic system

9084. The following statements are true about intravenous route of drug administration EXCEPT____________?
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A. Suspensions can be administered

B. Aseptic precautions are required

C. Bioavailability is 100%

D. It is useful in emergencies

9085. Which among the following is Not used for surface anesthesia ?
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A. Procaine

B. Lignocaine

C. Benzocaine

D. Tetracaine

9087. Naturally occurring local anaesthetic________________?
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A. Lignocaine

B. None of the above

C. Cocaine

D. Procaine

9088. Action of Nitroglycerin is______________?
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A. Blocks arrhythmia

B. Increases perfusion to heart

C. Slows SA node conductivity

D. Direct action on smooth muscle
9090. Which produces dissociative anaesthesia_____________?
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A. Propanidid

B. Fentany droperodol

C. Theiopentone sodium

D. Ketamine
9091. INFLIXIMAB (systemic) is used in_____________?
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A. All of the above

B. Crohns disease (treatment)

C. To reduce the number of draining enterocutaneous fistula(s) in patients with fistulizing crohns disease

D. Rheumatoid arthritis (treatment)

9092. Omeprazol is used in the treatment of____________?
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A. cholera

B. Peptic Ulcer

C. Amoebiasis

D. Malaria

9093. Doalin pectrose is_____________?
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A. Counter irritant

B. Mummifying agent

C. Anticoagulant

D. Anti diarroheal
9094. A young lady talking rifampicin and OCP together become pregnant, most probable cause is____________?
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A. Increase excretion of OCPs

B. Obstruction of fallopian tubes

C. Rifampicin causes hepatic enzyme induction and increase metabolism of OCPs

D. Decreased absorption of OCPs

9095. A side effect of an antithyroid drug is______________?
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A. Tremors

B. Hypotension

C. Obesity

D. Hypothyroidism
9096. Therapetic index indicates____________?
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A. Drug safety

B. Drug toxicty

C. Drugs Lethal effect

D. Drug potency

9097. Which statement is true about carbamazepine ?
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A. It is the drug of choice for status epilepticus

B. Used in trigeminal neuralgia

C. Carbamazepine is an enzyme inhibitor

D. Can cause megaloblastic anemia