9101. Majority of drugs are transported across the membrane by____________?
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A. Active transport

B. Filtration

C. Facilitated trasnsport

D. Passive diffusion
9102. An attack of migraine can be easily terminated by___________?
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A. Morphine

B. Ibuprofen

C. Acetylcholine

D. Ergotamine
9103. One of the following is not an antiemetic_____________?
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A. Chlorpromazine

B. Metaclopromide

C. Digitoxin

D. Scopolamine

9104. Xerostomia is treated with_____________?
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A. Atropine

B. Scopalamine

C. Ephedrine

D. Neostigmine
9105. Buprenorphine acts by following mechanism________________?
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A. Mu receptor partial agnoist

B. Kappa receptor partial agonist

C. Kappa receptor antagonist

D. Mu receptor antagonist

9106. Problems associated with nitrous oxide anaesthesia is_____________?
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A. Tachycardia and or arrhythmias

B. Behavioral problem

C. Sensitizes the heart to adrenaline

D. Prolonged difficult induction

9107. One of the benzodiazepines (BDZ) comparatively safe in pregnancy is (Category-B) ?
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A. None of the above

B. Alprozolam

C. Zolpidem

D. Lorazepam
9108. Which of the following second generation anti-histaminics is used topically______________?
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A. Cetrizine

B. Terfenadine

C. Acrivastine

D. Lovocabastine

9109. Which of the following drugs to not require a change in their dosage in patients with renal failure_______________?
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A. Cefotaxime

B. Isoniazid

C. Aminoglycoside

D. Rifampicin

9110. Drug not requiring dose adjustment in renal disease is___________?
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A. Aminoglycoside

B. Calcium channel blocker

C. Vancomycin

D. Metronidazole

9111. Salicylate overdose in children causes_______________?
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A. Crystalluria

B. None of the above

C. Kernicterus

D. Ryes syndrome
9112. A drug A & B compared, all are true except____________?
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A. 1 mg of A cause effect not even caused by maximum tolerated dose of B, so drug A is more efficacious

B. Efficacy is not dose dependent

C. 1 mg of A cause effect not caused by 1 mg of B so A is more efficacious

D. 1 mg of A causes same effect of 3 mg of B, so A is more potent

9113. Patients tend to exhibit a greater than normal response drugs in each of the following conditions except_______________?
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A. Congestive cardiac failure

B. Hypolbuminaemia

C. Hepartic cirrhossis

D. Hyperthyroidism

9114. Which of the following is not caused by Frusemide____________?
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A. Hypercalcemia

B. Hyperuricemia

C. Hypokalemia

D. Hyponatremia

9115. Intramuscular route is precluded during the medication of________________?
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A. Anticoagulants

B. Anti-hypertensives

C. Anti-diabetics

D. Anti-fibrinolytics

9116. The vulnerable period of pregnancy for the causation of foetal malformation is_____________?
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A. 1 18 days

B. 19 55 days

C. 56 85 days

D. II trimester

9117. Mention the drug causing gynecomastia hirsuitism, menstrual disturbance on long-term use______________?
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A. Acetazolamide

B. Hydrochlorthiazide

C. Amiloride

D. Spironolactone
9118. Which of the following anesthetic drugs produces powerful stimulation of the cerebral cortex_____________?
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A. Procaine

B. Lidocaine

C. Tetracaine

D. Cocaine
9119. Respiratory depression is seen with_____________?
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A. Antidepressants

B. Tranquilizers

C. Synthetic narcotics

D. Non-barbiturates

9120. Imatinib acts on______________?
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A. Inhibits Phosphodiesterase

B. Alpha TNF receptors

C. IL-2 receptors

D. Tyrosin Kinase receptors
9121. Ketamine is a________________?
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A. Antidepressive agent

B. Short general anesthetic agent

C. Local anesthetic agent

D. Hypnotic agent

9122. B- blocker with additional a-blocking property is____________?
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A. Timolol

B. Propranolol

C. Metoprolol

D. Labetalol
9123. In the second stage of anesthesia the pupil is_______________?
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A. Normal in size

B. Totally dilated

C. Constricted

D. Partially dilated
9124. The organ most resistant to GA is______________?
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A. Spinal Cord

B. Medulla oblonagata

C. Cerebrum

D. Medullary cortex

9125. Neuro adaptation to drug is same as______________?
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A. Habituation

B. Psychological dependence

C. Physical dependence

D. Addiction

9126. The drug which has an antabusive effect when alcohol is ingested is______________?
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A. Metronidazole

B. Penicillin G

C. Clindamycin

D. Doxycycline

9127. Long acting beta 2 agonist ?
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A. Albuterol

B. Pirlbuterol

C. Orciprenaline

D. Salmeterol
9128. Which of the following is an ACE inhibitor ?
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A. Spirino lactone

B. Saralosin

C. Coptopril

D. Diltiazem

9129. An antiepileptic drug used in petitmal epilepsy is______________?
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A. Phenobarbitonse

B. Dilantoin sodium

C. Ethosuximide

D. Diazepam

9130. Prolonged use of aspirin causes_______________?
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A. Hyprphosphatasia

B. Hypoprothrombinemia

C. Hypercalcemia

D. Hyperprothrombinemia

9131. Toxic optic neuropathy can be caused by all of the following EXCEPT_______________?
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A. Ethylene glycol

B. Ethambutol

C. Tetracycline

D. Ciprofloxacin
9132. IF patient suffered from exaggerated effect of pharmacological effect____________?
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A. Side effect

B. Idosyncrasy

C. Toxicity

D. None of the above

9133. Which of the following cannot be used as a surface local anaesthetics ?
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A. Benzocaine

B. Lidocaine

C. Tetracaine

D. Procaine
9134. Which of the following is not a potassium sparing diuretic______________?
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A. Amelioride

B. Triamtrence

C. Spironolactone

D. Bumetainde
9135. The statement Not true of Selective Cox 2 inhibitor is________________?
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A. Fewer incidence of gastrointestinal side effect

B. Safe in patients with renal insufficiency

C. The analgesic and anti-inflammatory effects identical to that of Non-selective NSAID

D. They do not offer the cardio protective effect

9136. Teratogenicity results when drugs are given during____________?
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A. Soon after birth

B. First trimester

C. Third trimester

D. Second trimester

9137. Which of the following is a protective drug in the management of gastric and duodenal ulcers ?
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A. Famotidine

B. NaHCO3

C. Carbenoxolone

D. H2 antihistamines

9138. Which of the following is antiasthmatic_____________?
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A. Acetylcholine

B. Serotonin

C. Histamine

D. Salbutamol
9139. Each of the following is correct for the treatment of Diarrhoea except_______________?
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A. Kaolin has marginal therapeutic effect

B. Diphenoxylate may cause respiratory depression on administration

C. Opioids delay the passage of gut contents by decreasing peristalsis and increasing intestinal segmentation

D. Loperamide had high abuse potential

9140. A patient on digoxin should not be given quindine because______________?
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A. Displaces digoxin from its protein binding sites

B. Decrease the renal clearance of digoxin

C. Decreases the plasma potassium level

D. Displaces digoxine from its tissue binding sites
9141. Which one of the following is Not true of angiotensin converting enzyme (ACE) inhibitor____________?
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A. Contraindicated in diabetic nephropathy

B. May cause hyperkalaemia in diabetic patients

C. NSAIDs may impair its hypotensive effect

D. Contraindicated in pregnancy

9142. ovidone iodine is the choice of mouthrinse in cases associated AIDS because______________?
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A. It is a topical anesthestic

B. All of the above

C. Its ability to aid in blood coagulation

D. It is a topical antimicrobial
9143. Which of the following drug is used to counter act the gastric irritation produced by administration of NSAID_______________?
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A. Betaxolol

B. Misoprostol

C. Pirenzipine

D. Roxatidine

9144. Acute Barbiturate poisoning results in_______________?
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A. Liver failure

B. Respiratory failure

C. Renal failure

D. Convulsions

9145. Omeprazole is a_____________?
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A. Antihistamine

B. Ulcer protective

C. Proton pump inhibitor

D. Ulcer healing drug

9146. The drug which has an affinity for a receptor site and produces the intrinsic activity of the receptor cell or enzyme system is known as____________?
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A. A non competitive antagonist

B. An agonist

C. A competitive antagonist

D. A physiologic antagonist

9147. Drug binds to activate the receptor is same fashion, which directly or indirectly brings effect, is_____________?
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A. Antagonist

B. Agonist

C. Partial agonist

D. Inverse agonist

9148. A child has phocomelia, this impliments his mother had taken which of the following medication during pregnancy______________?
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A. Chloroquine

B. Thalidomide

C. Tetracycline

D. Warfarin

9149. Following inhibits Cytochrome P450_____________?
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A. Ranitidine

B. Famotidine

C. Cimetidine

D. All of the above

9150. Therapeutic uses of calcium salts include the following except_________________?
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A. Disorders of coagulation

B. Osteoporosis

C. Extreme hyper-Kalemia

D. Laryngospasm