9002. BEnzodiazepines are true in___________________?
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A. All have metabolically active substrates

B. After metabolism of other drugs in liver

C. Produce distortion in sleep more than other sedatives

D. More safe than other sedatives when take in larger amounts
9003. Aspirin produces all of the following effects except_____________?
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A. Frank gastric bleeding

B. Prolonged prothrombin time

C. Platelet dysfunction

D. Constipation
9004. An attack of bronchial asthma is most likely to be triggered by________________?
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A. Aspirin

B. Ibuprufen

C. Diclofenac potassium

D. Mefenamic acid

E. Both A & B
9005. Aspirine cause_____________?
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A. Increase APTT

B. Increase PTT

C. Increase CT

D. Increase BT
9006. Which among the following is a pure antagonist of opioid receptors ?
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A. Natrexone

B. Pentazonice

C. Nalbuphine

D. Butorphanol

9007. Which of the following is a muscle relaxant_________________?
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A. Pentazocine

B. Phenylephrine

C. Hyoscin

D. Scoline

9009. Which of the following is a short acting barbiturate ?
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A. Phenobarbita

B. Secobarbital

C. Diazepam

D. Pentobarbital

9010. Paracetamol is contraindicated in_______________?
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A. Chronic hepatitis

B. Bleeding disorders

C. Nephritis

D. A & B
9012. Prolonged use of aspirin leads to______________?
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A. Bleeding defects

B. peptic ulcer

C. Carcinoma

D. A & B
9013. Which of the following opioids is not given intrathecally ?
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A. Sufentanil

B. Fentanyl

C. Remifentanil

D. Morphine

9014. Aspirin causes___________?
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A. Aplastic anemia

B. Hypoprothrombinemia

C. Agranulocytosis

D. Hemolytic anemia

9015. Aspirin is used in treatment of Myocardial Infarction___________?
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A. It stimulates Prostacyclins

B. It is a vasodilator

C. It inhibits thromboxanes

D. Ithelps in reducing inflammatory aggregate

9016. Activation of which of the following receptors would be expected to decrease anxiety_____________?
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A. Nicotinic cholinergic receptors

B. Glutamate receptors

C. Glucocorticoid receptors

D. GABA receptors
9018. Which of the following drug induces parkinsonism ?
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A. Chlorpromazine

B. Chloroquine

C. Chlorpheniramine

D. Chlorhexidine

9019. Atypical Antipsychotic are all except______________?
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A. Olanzepine

B. Thioridazone

C. Risperidone

D. Clozapine

9020. Benzodiazepine antagonist is________________?
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A. Naltrexone

B. Furazolidone

C. Naloxone

D. Flumazenil
9021. DOPA and 5-Hydroxytryptophan are clinically important because_____________?
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A. They act as neuromodulators

B. They cross blood Brain Barriers

C. They are acidic precursors of Brain amines

D. They are metabolites of various neurogenic amines

9022. All of the following statements about pain are correct except_____________?
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A. NSAIDS benefit by preventing prostaglandin synthesis

B. Analgesia is associated with ? and k receptors

C. Naloxane is a non-competitive antagonist and irreversibly opposes the opioids

D. Dysphoria is associated with S receptors

9023. Drug that does not cause sedation________________?
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A. Zopiclone

B. Diazepam

C. Buspirone

D. Nitrazepam

9026. Phenytoin is associated with_____________?
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A. Alzhiemers disease

B. Cushings syndrome

C. Vitamin C deficiency

D. Folic acid deficiency
9027. Phenothiazines are used to____________?
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A. Produce analgesia

B. Alter psychotic behaviour

C. Suppress coughing

D. Produce muscle relaxation

9028. Aspirine is useful in all the following conditions EXCEPT_____________?
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A. Gout

B. Fever

C. Post myocardial infarction

D. Venous thrombosis

9029. A paralyzing dose of succinylcholine initially elicits______________?
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A. Muscle fasciculation

B. CNS stimulation

C. CNS depression

D. Decreased salivation

9030. Drug which is used to control status epilepticus is______________?
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A. Pheno barbital

B. Diazepam

C. Sodium nitroprusside

D. Glyceryl trinitrite

9031. The beneficial effect of drug neostigmine in the treatment of Myasthenia gravis is due to the action____________?
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A. It produces more acetycholine receptors

B. It increases the action of cholinesterase

C. It is produces more acetylcholine

D. It inhibits the action of cholinesterase
9032. In which of the following stage general anesthesia surgery is done_______________?
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A. Stage III plane 3

B. Stage I

C. Stage II

D. Stage III plane 2

9033. Nitrates are not used in______________?
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A. Esophageal spasm

B. Cyanide poisoning

C. CCF

D. Renal colic
9035. Drug efficacy refers to_________________?
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A. The therapeutic index of the drug

B. Range of disease in which the drug beneficial

C. The therapeutic does range of the drug

D. Maximal intensity of response that can be produced by the drug
9038. Which of the following is true for carbonic anhydrase inhibitor ?
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A. It causes excertion of Na & Cl

B. It causes metabolic alkalosis

C. It is very potent

D. It is used as an adjunct in epilepsy
9040. The most common type of epilepsy in children is________________?
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A. Infantile spasm

B. Grand mal epilepsy

C. Petit mal

D. None of the above

9041. According to American society of Anesthetists, physical status scale Class III would be_____________?
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A. A normal healthy individual

B. A patient with severe systemic disease that it not in capacitating

C. A patient with mild systemic disease

D. None of the above

9042. Idiosyncracy is known as to have_____________?
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A. Genetic component

B. Nutritional component

C. Psychological component

D. Psysiological component

9043. The ratio of the median lethal dose of the median effective dose is the_____________?
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A. Morbidity index

B. Therapeutic index

C. Moratality index

D. Anesthetic ratio

9044. Which of the following is not an antimigraine agent ?
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A. Flunarizine

B. Propanolol

C. Divalprox sodium

D. Zonisamide
9046. Drug which crosses placental barrier is____________?
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A. All of the above

B. phenytoin

C. Corticosteroids

D. Diazepam

9047. Digitalis induced automaticity is enhanced by______________?
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A. Low K+ levels

B. High K+ levels

C. High Na+ levels

D. High Ca2+ levels

9048. Which of the following is NOT a systemic effect of corticosteroid ?
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A. Increase in total amount of circulatory neutrophils

B. Increase in IL-1

C. Anti-inflammatory effect is increased

D. Inhibit phospholipase A2

9049. Hallucinations are seen after ________ anesthesia?
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A. Thiopentone

B. Ketamine

C. Nitrous oxide

D. Tentanyl

9050. A patient on 300 mg of aspirin will show all the following except________________?
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A. Irreversible inhibition of cyclooxygenase path way

B. Inhibition of thromboxane TXA2

C. Prolonged bleeding time

D. Inhibition of prostaglandin PGI2