biochemistry MCQs – Page 7

Practise focused biochemistry questions with marked answers for exam preparation and subject revision.

biochemistry Mcqs
301. Most of vitamin B12 in the body is stored as_____________?
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A. Hydroxy B12

B. Methyl B12

C. None of the above

D. Cyano cobalamine

302. Endogenous triglycerides in plasma is maximally bound to________________?
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A. HDL

B. Chylomicrons

C. LDL

D. VLDL
303. The following is not a phospholipid______________?
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A. Cephalin

B. Cerebroside

C. Lecithin

D. Sphingomyelin

304. Avidin influences which of the following vitamins ?
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A. Phylloquinone

B. Biotin

C. Thiamine

D. Niacin

305. Vitamin B12 is_______________?
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A. Extrinsic factor of castle

B. Intrinsic factor of castle

C. A fat soluble vitamin

D. Cyano cobalamine

306. Digestion of proteins is initiated by________________?
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A. Amylase

B. Pepsin

C. Sucrase

D. Chymotrypsin

307. The lipoprotein particles that have the highest percentage concentration of cholesterol is_______________?
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A. LDL (Low density lipoprotein)

B. HDL (High density lipoprotein)

C. VLDL (Very low density lipoprotein)

D. Chylomicron

308. Deficiency of vitamin C causes the following except_______________?
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A. Defective collagen synthesis

B. Subcutaneous & other hemorrhage

C. Pigeon chest

D. Soft swollen gums

309. Transport form of iron is______________?
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A. Transferrin

B. Lactoferrin

C. Apoferritin

D. Ferritin

310. Nonsense codons bring about__________________?
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A. Initiation of protein synthesis

B. Elongation of polypeptide chain

C. Pre-translational modification of protein

D. Termination of protein synthesis
311. Decarboxylation of which of the following amino acids results in formation of a vasodilator ?
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A. Arginine

B. Glutamic acid

C. Histidine

D. Valine

312. Denaturation of double stranded DNA involves_______________?
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A. It gets broken down to nucleotides

B. It becomes double stranded irreversibly

C. It becomes single stranded irreversibly

D. It becomes single stranded reversibly
313. The fuel value of fat is____________?
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A. 7

B. 4

C. 5

D. 9
314. Amino acids excreted in the urine in cystinosis______________?
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A. Cystine

B. All of the above

C. Ornithine

D. Arginine

E. Lysine

315. Proteins are linear polymers of amino acids, They fold into compact structures Sometimes these folded structures associate to form homo or hetero dimers Which one of the following refers to this associated form ?
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A. Denatured state

B. Quaternary structure

C. Precipitation

D. Molecular aggregation

316. In human body which of the following trace element is next to iron_______________?
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A. Zn++

B. Cu++

C. Ca++

D. Selenium

317. Unwinding of DNA is done by____________?
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A. Ligase

B. DNAse

C. Topo isomerase

D. Reverse transcriptase

318. All are true about glutathione except ?
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A. It converts hemoglobin to methemoglobin

B. It is a tripetide

C. It scavenges free radicals and superoxide ions

D. It conjugates xenobiotics

319. Normal serum calcium level is_______________?
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A. 19-21 mg/dl

B. 9-11 mg/dl

C. 20-30 mg/dl

D. 4-6 mg/dl

320. Codons are present on_____________?
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A. DNA

B. m-RNA

C. t-RNA

D. Ribosomal RNA

321. The amino acid, which is used is the estimation of collagen is_____________?
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A. Proline

B. Lysine

C. Glycine

D. Hydroxyproline
322. In molecular cloning, Blue White screening is used for_______________?
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A. To identify desired chromosomal DNA insert in plasmid vectors

B. To screen for recombinant vectors

C. To detect host DNA in situ

D. To detect gene mutations

323. Inside the cell, the substance, which contributes to most of the osmolality, is________________?
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A. Protein

B. Phosphate

C. Potassium

D. Urea

324. The action of vitamin K in formation of clotting factor is through__________________?
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A. Golgi complex

B. Endoplasmic reticulum

C. Post translation

D. Post transcription

325. Vitamin C is present in largest amount in the body in____________?
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A. Kidneys

B. Testes

C. Adrenal cortex

D. Eye

326. Mutations are due to changes in_________________?
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A. Amino acid sequence of ribonuclease

B. RNA nucleotide sequence

C. Cell walls

D. DNA nucleotide sequence
327. The sugar component of cerebrosides is_____________?
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A. Galactose

B. Fructose

C. None of the above

D. Sucrose

328. The normal value of serum potassium level is____________?
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A. 3.8-5 meq/L

B. 6-7.2 meq/L

C. 2.8-3.8 meq/L

D. 5-5.8 meq/L

329. The main pathway for De Novo synthesis of fatty acids occurs in_______________?
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A. Nucleus

B. Mitochondria

C. None of the above

D. Cytosol
330. All are components of basement membrane except________________?
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A. Laminin

B. nidogen

C. Eutactin

D. Rhodopsin
331. Who is known for his work on scurvy ?
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A. Fracastorius

B. Edward Jenner

C. James lind

D. John snow

332. NADPH is required for________________?
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A. Fatty acid synthesis

B. Glycolysis

C. Gluconeogenesis

D. Glycogenolysis

333. True about G protein couple receptors is _________________ ?
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A. G proteins bind to hormones on the cell surface

B. G Proteins act as inhibitory and excitatory because of difference in alpha subunit

C. All the three subunits alpha, beta and gamma should bind each other for G protein to act

D. G protein is bound to GTP in resting state

334. HMG-CoA is formed during metabolism of all except______________?
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A. Ketone bodies

B. Leucine

C. Bile acids

D. Cholesterol

335. Quaternary structure of protein is_____________?
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A. The inter relation and arrangement of polypeptides in a protein with more than 2 polypeptide chains

B. Inter relation of amino acids in 2 polypeptide chains

C. Inter relation between amino acids in a single polypeptide chain

D. The arrangement sequence of amino acids in the polypeptide chain

336. Which of the following process in involved in conversion of DNA to RNA___________?
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A. Translocation

B. Conjugation

C. Transcription

D. Transduction

337. A mutation that converts an amino acid codon to a stop codon is a_____________?
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A. Silent mutation

B. Transversion

C. Nonsense mutation

D. Frame shift mutation

338. Ketone bodies are normally synthesized from______________?
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A. Glucose

B. Acetyl-CoA

C. Acetone

D. Glycerol

339. All of the following are true about manifestations of vitamin E deficiency except_____________?
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A. Posterior column abnormalities

B. Cerebellar ataxia

C. Hemolytic anemia

D. Autonomic dysfunctions
340. Hydroxylation of proline require the following except____________?
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A. O2

B. Fe+2

C. Ascorbic acid

D. Succinate
341. Rate limiting step in cholesterol synthesis is_______________?
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A. HMG CoA lyase

B. HMG CoA reductase

C. Mevalonate synthetase

D. HMG CoA synthetase

342. The transmembrane adhesive molecules present in hemi desmosomes which specifically binds to basal lamina glycoprotein laminin are______________?
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A. a and B catenin

B. The catenins desmoplakin

C. Integrin a6-B4

D. cadherins desmoglein

343. Which of the following is a precursor of protoporphyrin_______________?
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A. Glycine

B. Leucine

C. Alanine

D. Histidine

344. The vitamin K dependent proteins C and S are characterized by their ability to inactivate factor_____________?
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A. VIII a

B. VIII a and V a

C. None of the above

D. V a

345. A fatty acid that is not synthesized in man is_____________?
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A. Palmitic acid

B. Oleic acid

C. Stearic acid

D. Linoleic acid
346. Argentaffinoma is characterized by excess excretion of_____________?
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A. 5- Hydroxy indole acetate

B. 3- Hydroxy phenyl pyruvate

C. Phenyl acetate

D. Phenyl lactate

347. The portion of DNA in Which RNA polymerase binds and starts transcription is called______________?
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A. Operator

B. Terminator

C. Anti terminator

D. Promoter region
348. The reducing equivalent for fatty acid synthesis is derived form____________?
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A. Krebs cycle

B. Urea cycle

C. Glycolysis

D. Pentose phosphate pathway
349. The ketone bodies, which are excreted in diabetic ketoacidosis ?
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A. Acetoacetic acid and oxalocacetic acid

B. Acetoacetic acid and pyruvic acid

C. Acetoacetic acid and beta hydroxyl butyric acid

D. Acetoacetic acid and alpha ketoglutaric acid

350. Under metabolic conditions associated with a high rate of fatty acid oxidation liver produces________________?
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A. Acetoacetate

B. Cholesterol

C. Glutamate

D. Glycine