biochemistry MCQs – Page 5

Practise focused biochemistry questions with marked answers for exam preparation and subject revision.

biochemistry Mcqs
201. In maple syrup urine disease the amino acids excreted in the urine are______________?
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A. Leucine

B. Isoleucine

C. All of the above

D. Valine

202. Which of the following is the best site of absorption of calcium ?
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A. Ascending colon

B. Proximal segment of small intestine

C. Middle segment of small intestine

D. Ileum

203. DNA double helix is bound by_____________?
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A. Covalent bond

B. Vander wall forces

C. Disulfide linkage

D. Hydrogen bond
204. In the physiological system, nitric oxide is known to act through_______________?
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A. Calcium ions

B. Cyclic GMP

C. Prostacyclins

D. Cyclic AMP

205. Thiamine deficiency can be diagnosed by measuring________________?
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A. Alkaline phosphatase levels in blood

B. Plasma pyruvate and lactic acid levels

C. Thiamine levels in blood

D. Transketolase activity in RBC
206. Cholesterol levels in abnormal person should be preferably less than_____________?
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A. 180 mg/dl

B. 150 mg/dl

C. 120 mg/dl

D. 200 mg/dl
207. Albumins and globulins are ________ proteins?
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A. Peptones

B. Prolamines

C. Lactalbumin

D. Simple
208. Cytochromes are_____________?
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A. Metal containing flavoproteins

B. Iron-porphyrin proteins

C. Pyridine nucleotides

D. Riboflavin containing nucleotides

209. One of the following is nonessential amino acid______________?
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A. Cystine

B. Valine

C. Methionine

D. Tyrosine
210. Which of these is not included in parenteral therapy ?
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A. Carbohydrates

B. Fibres

C. Fats

D. Micronutrients

211. Biotin is required for the activity of_______________?
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A. Lactate dehydrogenase

B. Phosphohexose isomerase

C. Pyruvate carboxylase

D. Succinate thiokinase

212. The lipid, which acumulates in fatty liver, is_______________?
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A. Lipoprotein

B. FFA

C. Triglycerides

D. Cholesterol

213. Glycine is present in____________?
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A. Purines

B. Creatine

C. All of the above

D. Glutathione

E. Hemoglobin

214. Non essential amino acids are not_____________?
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A. Required in the diet

B. Used by the body

C. Absorbed in the intestines

D. Forming part of the proteins

215. The total blood concentration of ketone bodies in well fed individual is__________?
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A. 20 mg%

B. 5 mg%

C. 12 mg%

D. 1 mg%
216. Within the RBC hypoxia stimulates glycolysis by which of the following regulating pathways ?
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A. Hypoxia inhibits hexokinase

B. Hypoxia stimulates release of all glycolytic enzymes from Band 3 on RBC membrane

C. Activation of the regulatory enzymes by high PH

D. Hypoxia stimulates pyruvate dehydrogenase by increased, 2, 3DPG

217. Enzyme regulating the conversion of ethanol to acetaldehyde________________?
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A. Acetaldehyde dehydrogenase

B. Catalase

C. Alcohol dehydrogenase

D. Enolase

218. True about denaturation of protein is all except______________?
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A. Disruption of secondary structure occurs

B. Biological activity is retained

C. Unfolding occurs

D. Sequence of amino acids remain the same

219. Angular cheilosis is frequently associated with deficiency of______________?
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A. Riboflavin

B. Folic acid

C. Niacin

D. Thiamine

220. The initiation codon for protein synthesis is_____________?
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A. AUG

B. UUU

C. UAA

D. UAG

221. End product of purine metabolism is______________?
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A. Creatinine

B. Xanthine

C. Phosphates

D. Uric acid
222. Transcription is the synthesis of____________?
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A. Double stranded complimentary copy of DNA

B. Complimentary copy of RNA

C. Single stranded complimentary copy of DNA

D. COmplimentary copy of rRNA

223. The following is not a carrier protein________________?
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A. Haptoglobulin

B. Cerruloplasmin

C. Transferrin

D. Transcobalamine

224. HMG CoA reductase is inhibited by_____________?
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A. Clofibrate

B. cholestyramine

C. Gemfibrosil

D. Lovastatin
225. Which of the following is a derived a derived protein_____________?
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A. Lactalbumin

B. Peptones

C. Prolamines

D. Protamines

226. In the body, metabolism of 10 g of protein would produce approximately____________?
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A. 410 Kcal

B. 41 Kcal

C. 4100 Kcal

D. 1 Kcal

227. Albinism is a genetic disease that results in incomplete metabolism of______________?
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A. Cystine

B. Tyrosine

C. Histidine

D. Alanine

228. The human plasma lipoprotein containing the highest percentage of triacylglycerol by weight is______________?
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A. Chylomicrons

B. LDL

C. HDL

D. VLDL

229. Detoxification or protective synthesis occurs by____________?
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A. Oxidation

B. Any of the above

C. Reduction

D. Conjugation

230. Highest binding of iron in plasma is seen with___________?
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A. Hemoglobin

B. Ceruloplasmin

C. Ferritin

D. Transferrin
231. The class of amino acids that contains only non essential amino acids is_______________?
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A. Acidic

B. Aromatic

C. Basic

D. Branched chain

232. The nitrogen of the body is supplied by______________?
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A. Triacyl glycerol

B. Glucose

C. Lipids

D. Proteins
233. At PH 7 the binding of 2,3 DPG to hemoglobin occurs at which site ?
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A. Sulphydryl group

B. Amino terminal

C. Carboxy terminal

D. Histidine

234. Thyroxine and catecholamines are derived from_____________?
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A. Tyrosine

B. Alanine

C. Tryptophan

D. Leucine

235. Ketone bodies are by products of metabolism of_____________?
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A. Fat

B. Protein

C. Carbohydrate

D. All of the above

236. Which is not seen in HMG CoA pathway ?
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A. Mevalonate

B. Pyruvate

C. Cholesterol

D. Acetyl CoA

237. The best technique useful for initial viral load estimation is________________?
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A. Electrophoresis

B. Widal test

C. Real time PCR

D. Immunofluoresence

238. The sigma subunit of prokaryotic RNA polymerase_______________?
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A. Specifically recognizes the promoter site

B. Is inhibited by a-amanitin

C. Binds the antibiotic Rifampicin

D. Is part of the core enzyme

239. Which of the following amino acids is quickly converted to tyrosine ?
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A. Glycine

B. Phenylalanine

C. Arginine

D. Leucine

240. Free radicals are chemical species which have______________?
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A. Single unpaired electron in an outer orbit

B. Double paired electron in an outer orbit

C. Double unpaired electron in an outer orbit

D. Single paired electron in an outer orbit

241. Restriction endonuclease cleaves______________?
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A. Polypeptide

B. SIngle stranded RNA

C. Double stranded DNA

D. SIngle stranded DNA

242. Which of the following is correct about breakdown of hemoglobin (Hb)_____________?
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A. Heme?Hb?Biliverdin?Urobilinogen

B. Hb?Heme?bilirubin?Urobilinogen?Biliverdin

C. Hb?Heme?bilirubin?Urobilinogen

D. Hb?Heme?Bilverdin?Uro bilinogen
243. In Niemann-Picks disease the following substrance accumulate in CNS in excess______________?
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A. Phosphoinositides

B. Glycerophosphatides

C. Phosphosphingosides

D. Glycerosphingosides

244. A small Ca+2 binding protein that modifies the activity of many enzymes and other proteins in response to changes of Ca+2 concentration is known as______________?
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A. Kinesin

B. Calmodulin

C. Collagen

D. Cycline

245. Glycemic index of a starchy food is a measure of its________________?
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A. None of the above

B. Collectivity

C. Utility

D. Energy

246. The amino acid residue having animino side chain is____________?
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A. Tyrosine

B. Proline

C. Histidine

D. Lysine

247. Fatty acid oxidation occurs in______________?
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A. Microsomes

B. All of the above

C. Mitochondria

D. Cytoplasm

248. Which of the following factors delay wound healing____________?
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A. B & C option

B. Ascorbic acid deficiency

C. Vitamin B12 deficiency

D. Infection

249. The product of oxidation of odd chainfatty acids is______________?
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A. Propionyl CoA

B. Fumaryl CoA

C. Aceto acetyl CoA

D. Malonyl CoA

250. R-RNA is mainly produced mainly in___________?
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A. Ribosome

B. Nucleolus

C. Endoplasmic reticulum

D. Nucleus