9401. Mechanism of action of chlortetracycline_____________?
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A. Interfere with metabolism

B. Interfere with DNA function

C. Inhibition of cell wall formation

D. Inhibition of protein synthesis
9405. True about amoxycillin in comparison to ampicillin is_______________?
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A. Lower oral biovailability

B. Can be given Parenterally

C. Higher oral biovailability

D. Equal oral biovailability

9406. One of the below mentioned penicillin is NOT given orally______________?
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A. Cloxacillin

B. Amoxicillin

C. Phenoxymethy penicillin

D. Carbenicillin
9407. The administration of penicillin G along with probenicid result in_____________?
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A. Increased metabolis of penciling G

B. Decreased renal excretion of penciling G

C. Increased excretion of probenacid in the feaces and perspiration

D. Increased excretion of probenacid in urine

9409. Sialogouges are______________?
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A. Decrease salivary secreations

B. Indicator dye for sialography

C. Increases salivary secretions

D. Medication for over function

9410. Cyclosporin is used an______________?
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A. Antiarrythmic

B. Anticancer drug

C. Immunosuppresant

D. Antibiotic

9411. Hypokalemia is seen in therapy with____________?
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A. Ibuprufen

B. Corticosteroids

C. Digitalis

D. Diazepam

9413. Not true about piperacilline is_______________?
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A. It is a ureido penicillin

B. Given parenterally

C. Inhibits Beta-lactamase

D. Active against pseudomonas aeruginose

9414. The principle therapeutic action of the glucocorticoid is________________?
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A. Antianabolic

B. Antidiuretic

C. Anti-inflammatory

D. Anti-infective

9415. Quindine is used to treat______________?
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A. Congestive heart failure

B. Angina pectoris

C. Hypertension

D. Atrial fibrillation
9416. Redman syndrome is side effect of______________?
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A. Chloramphenicol

B. Rifampicin

C. Vancomycin

D. Tetracycline

9417. Tetracycline when given to pregnant woman can cause_______________?
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A. Acute hepatic necrosis

B. Increased intracranial pressure in infant

C. Discoloration/ staining of hard structures of foetus

D. All of the above

9418. All of the following statement about antimalarial drugs are correct except_____________?
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A. Primaquine is liable to cause hemolysis in patients with G6PD deficiency

B. Primaquine eliminates P. vivax and P. ovale

C. Halofantrine prolongs QT interval and causes dysarrythmia

D. Mefloquine may safely be given to air pilots
9419. All of the following are therapeutic uses of penicillin G, except_____________?
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A. Rickettsial infection

B. Syphilis

C. Bacterial meningitis

D. Anthrax

9420. The toxic effect of Beta receptor antagonists includes all the following EXCEPT____________?
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A. Precipitate migrainic effect

B. Worsening of preexisting asthma

C. Hypoglycemic episodes in diabetes

D. Ischemic cardiac episode on abrupt discontinuation

9421. Which anti tubercullar drug will cause transjent memory loss ?
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A. Enthionamide

B. Pyrazinamide

C. Ethambutol

D. INH
9422. various insulin preparations useful in the treatment of diabetes mellitus differ primarily in______________?
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A. Focus of action

B. Mode of biotransformation

C. Onset and duration of action

D. None of the above

9424. Identify the drugs useful against pseudomonanas infection______________?
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A. Ceftazidine

B. Ticarcillin

C. All of the above

D. Amoxycillin

9425. Triflusal is a___________________?
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A. Antibiotic

B. Anti-arthritic drug

C. Anti-inflaqmmatory drug

D. Antiplatelet drug
9426. Metronidazole______________?
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A. Is active against gram-positive aerobes

B. Is mainly concentrated in saliva

C. Has no side-effects

D. Is used in management of ANUG
9427. Which of the following group of drugs are a neuromuscular blocking agents_______________?
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A. Pancuronium, rocuronium

B. Pirenzipine, propanolol and propantheline

C. choline, adrenaline and amphetamine

D. Glycinium neostigamine and physostigamine

9429. Combination chemotherapy is used in tuberculosis in order to reduce____________?
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A. Cost of therapy

B. Dosage of drugs

C. Development of drug resistance

D. Side effects of drugs

9430. All of the following are true about tolbutamide except____________?
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A. It is used in type-I diabetes mellitus

B. It acts on pancreas to stimulate release of insulin

C. It is taken orally

D. It causes alcohol intolerance

9432. A potent non-texic anti-herpes drug is_______________?
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A. Acyclovir

B. Ara-amp

C. Idoxyuridine

D. Vidarabine

9433. Prolonged administration of streptomycin may result in damage to the____________?
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A. Facial nerve

B. Trigeminal nerve

C. Optic nerve

D. Auditory nerve
9434. The most serious side effect of drug chloramp henicol is______________?
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A. Bone marrow depression

B. Angioneurotic oedema

C. Photosensitivity

D. Candidiasis

9435. Which of the following is not uridopenicillin ?
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A. Mezlocillin

B. Azlocillin

C. Flucloxacillin

D. Piperacillin

9436. 1st generation cephalosporin is________________?
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A. Cefepime

B. Cephadroxil

C. Cefoperazone

D. Cefotaxime

9437. Which one of the following antibiotics chelates with calcium ?
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A. pencillin

B. Tetracycline

C. Cephalosporins

D. Erythromycin

9438. The drug which is contraindicated in haemophilla is_________________?
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A. Dipheny 1 hydantoin

B. Penicillinium

C. Amino epsilon caproic acid

D. Aspirin
9440. Cell wall synthesis is inhibited by all except____________?
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A. Cephalexin

B. Penicillin

C. Ampicillin

D. Lincomycin
9441. When broad spectrum antibiotics are administered with coumarin anticoagulants, the anticoagulant action may be____________?
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A. Reduced because of increased protein binding

B. Reduced because of enhanced hepatic drug metabolism

C. Increase because of decrease renal excretion of the anticoagulant

D. Increased because of reduction of vitamin sources
9442. All of the following are topically used sulphonamides except____________?
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A. Suphacetamide

B. Silversulphadiazine

C. Mafenide

D. Sulphadiazine
9443. If patient is given Noradrenaline what will happen_______________?
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A. Cause decrease in cardiac output and relax bradycardia

B. Cause increase in B.P, due to its action on Beta receptors only

C. None of the above

D. Cause decrease in B.P, due to its action on Alpha receptors only

9444. The mechanism of action of sodium nitroprusside is_____________?
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A. Block the sympathetic flow at hypothalamus

B. Direct Vasodilator

C. Increases cAMP

D. Calcium channel blocker

9445. Erythromycin is_______________?
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A. All of these

B. Cidal in action

C. Static in action

D. Cidal in high concentration
9446. Metronidazole is a type of___________?
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A. Quinolone

B. Antidepressant

C. Broad spectrum antibiotic

D. Imidazole derivative
9448. Which of the following combination of iron can be given both IM and IV____________?
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A. ferrous Sulphate

B. Iron Sorbitol Citrate Solution

C. Iron dextran

D. ferrous Humourate

9450. The aminoglycoside with least toxic effect is_____________?
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A. Isoniazid

B. Ethambutol

C. Streptomycin

D. Kanamycin