9351. In which of the following categories are ephedrine, tyramine and emphetamine classified________________?
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A. Direct acting sympathomimetics

B. Indirect acting sympathomimetics

C. Anticholinesterases

D. Alpha-adrenergic blocking agents

9352. All of the following cephalosporines are active against Pseudomonas Except_____________?
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A. Cefaclor

B. Ceftazidine

C. Cefotaxime

D. Cefoperazone

9353. Bacitracin is a_______________?
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A. Oral antibiotic

B. Topical antibiotic

C. All of the above

D. Parenteral antibiotic

9354. Drug chemically related to penicillins is_____________?
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A. Cephalosporin

B. Tetracycline

C. Lincemycin

D. Sulphonamide

9355. Which of the following statements is not correct regarding warfarin_____________?
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A. In a racemic mixture the R form is four times more active than the S form

B. Better avoided during pregnancy as it may causes skeletal deformity of the foetus

C. Transient hypercoagulability is seen

D. The anticoagulant effect is seen only after 72 hours of administration

9356. Which of the following drugs is used therapeutically during allergic conditions ?
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A. Succinylcholine

B. Epinephrine

C. Sulfonamides

D. Tetracycline

9357. Antibiotic that achieves high concentration in Hard tissue, because of its molecular size is______________?
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A. Clindamycin

B. Ciprofloxacin

C. Erythromycin

D. Ceftum

9358. Drug which is most unsafe during pregnancy is____________?
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A. Ethambutol

B. B & C

C. Streptomycin

D. Kanamycin

9359. Roxithromycin is______________?
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A. Long acting polypeptide

B. Short action quinolone

C. A long acting macrolide

D. Short acting macrolide

9360. Which of the following antibiotics is found at much higher concentrations in cervicular fluid than in serum ?
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A. Metronidazole

B. Tetracyline

C. Penicillin

D. Clindamycin

9361. Povidine iodine is used for_____________?
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A. Burns

B. All of the above

C. Tinea

D. Non-specific vaginitis

9362. Amphotericin B is given for what etiology_______________?
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A. Viral

B. Rickettesial

C. Bacterial

D. Fungal
9363. Concurrent administration of tetracyclines is most likely to impair the action of_____________?
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A. Penicillin

B. Erythromycin

C. Chloramphenicol

D. Lincomycin

9364. B-lactam antibiotics are_____________?
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A. Imipenem

B. All of the above

C. Penicillin

D. Cephalosporins

9365. While performing a procedure, a resident doctor injures herself with a suture needle that has been used to stitch a patient with HIV infection for 11 years. He has been complaint with therapy for several years and has recently changed tablets because of alteration in his appearance. His last CD4 count was 360 cells/mm. The doctor is offered post exposure prophylaxis. Which regimen should she take ?
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A. Ziduvidine and Lamivudine and Stavudine

B. Ziduvidine and Lamivudine and Indivair

C. Ziduvidine and Lamivudine and Abacavir

D. Ziduvidine and Lamivudine

9366. The following adverse effect of penicillin is dose related___________?
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A. Intersititial Nephritis

B. Drug fever

C. Skin rash

D. Encephalopathy
9367. The anticogulant of choice during pregnancy is______________?
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A. Sodium oxalate

B. Heparin

C. Phenindone

D. Warfarin sodium

9368. Which of the following is caused by Amphotericin B____________?
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A. Hyperkalemia

B. Hyponatremia

C. Hypermagnesemia

D. Hypo Kalemia
9369. An excess of which of the following hormones may be associated with increased sensitivity to epinephrine ?
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A. Parathyroid

B. Thyroid

C. Insulin

D. Testosterone

9370. Clavulanic acid added to ampicillin causes_____________?
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A. Increase effectivity against gram-positive organisms

B. Increase the effectiveness against delta lactamase producing organism

C. Increase effectivity against gram-negative organisms

D. Inhibition of B-lactamases
9371. Slufonamides mainly interferes with the bacterial______________?
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A. Translation

B. Transcription mechanisms

C. Ribosomal function

D. PABA
9372. Agents/Drugs which help in rapid coagulation of Blood_______________?
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A. Haemostatics

B. Astrigents

C. All of the above

D. Styptics

9373. Antifungal drug not used in the treatment of imtestinal candidiasis______________?
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A. Clotrimazole

B. Nystatin

C. Amphotericin

D. Ketoconazole

9374. All of the following have receptors which are transcription factors except____________?
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A. Vitamin D

B. Estrogen

C. Glucocorticoid

D. Insulin
9375. Ototoxicity and nephrotoxicity is caused by______________?
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A. antibiotic

B. Antifungal

C. Antiviral

D. Antiemetic

9376. Tetracyclines act by__________________?
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A. Inhibiting peptidyl transferase

B. Inactivating elongation factors

C. Inhibiting the binding of aminoacyl tRNA to the ribosomal complex

D. Causing misreading of mRNA

9377. In the treatment of intestinal of intestinal and extraintestinal amoebiasis which of the following drug is useful____________?
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A. Metronidazole

B. Cefaclor

C. Chloroquine

D. Diloxane

9378. Which of the following drug does not show renal toxicity_____________?
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A. Streptomycin

B. Gentamycin

C. Methoxyprenaline

D. Isoflurane
9379. Which of the following is a characteristic of tetracycline stains ?
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A. Stained teeth fluoresce light yellow under U.V light

B. Stains are dark brown in color

C. There is less deposition in dentine as compared to enamel

D. Is always accompanied by hypolastic defects

9380. One of the following is not penicillinase susceptible______________?
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A. Piperacillin

B. Cloxacillin

C. Penicillin G

D. Amoxicillin

9381. Role of Heparin_____________?
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A. Prevents synthesis of prothrombin

B. Prevents synthesis of fibrinogen

C. Prevents prothrombin conversion to thrombin

D. Prevents conversion of fibrinogen to fibrin

9382. Which of the following drugs is not hypoglycemic?
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A. Gluengon

B. Glibenclamide

C. Tolbutamide

D. Ethosuxinide

9383. The highest risk associated with use of oral contraceptives in________________?
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A. Permanent sterility

B. Thromboembolic disorders

C. Cancer of breast

D. Hepatic necrosis

9384. Which of the following receptors is activated by acetylcholine and blocked by atropine______________?
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A. Nicotinic

B. Beta 1 and 2

C. Alpha 1 and 2

D. Muscarinic
9385. All except one are centrally acting muscle blocks___________?
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A. Diazepam

B. Dantrolene sodium

C. Meprobamate

D. Baclofen

9386. Which among the drugs given below, does Not act by protease inhibition ?
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A. Saquinavir

B. Ritonavir

C. Zanamivir

D. Nelfinavir

9387. The drug of choice for treatment of tyhoid is____________?
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A. Metronidazole

B. Ciprofloxacin

C. Tetracycline

D. Cefotaxim

9388. All of the following drugs are components of the MOPP cancer Chemotherapy regimen EXCEPT______________?
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A. Procarbazine

B. Methotrexate

C. Vincristine

D. Mechlorethamine

9389. Oral contraceptive failure occurs in a patient on Rifampicin because of____________?
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A. Rifampicin induce the metabolism of contra ceptive

B. Rifampicin antagonize the action of oral contraceptive

C. Rifampicin simulates gonadotropin relase from pituitary

D. Rifampicin decrease the secretion of progestin

9390. The bacterial resistance to tetracycline is due to___________?
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A. Decreased uptake of drug by bacteria

B. Alteration of dehydrofolate reductase

C. Inactivation of drug by enzymes

D. Alteration of drug binding sites

9391. Which of the following drugs in likely to damage the eighth cranial nerve when administered for a long period of time ?
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A. Streptomycin

B. Ethambutol

C. Isoniazid

D. Rifampicin

9392. Morphine withdrawal is characterized by all EXCEPT_____________?
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A. Yawning

B. Diarrhoea

C. Lacrimation

D. Miosis
9393. First line of antitubercular drug is_____________?
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A. Ethambutol

B. INH

C. Streptomycin

D. Cephalosporins

9394. All of the following are features of streptomycin drug except______________?
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A. It is an antitubercular drug

B. Effective against g-ve organisms

C. It can be given orally

D. None of the above

9395. Agent used in oral thrush_____________?
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A. Miconazole

B. Amoxycillin

C. Clobetasol

D. Clotrimazole
9396. Scopolamine helps in________________?
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A. A & C

B. Decreased secretions

C. Motion sickness

D. Hypertension

9397. Which of the following is not a broad spectrum antibiotic ?
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A. Tetracycline

B. Chloramphenicol

C. Cephalosporins

D. Doxycyclin

9398. Morphine is a_____________?
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A. Sedative

B. Alkaloid

C. Diuretic

D. Anti hypertensive

E. Both A & B
9399. Excessive bleeding due to heparin overdose is controlled by______________?
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A. Factor VIII

B. Vitamin K

C. Protamine sultate

D. EADA

9400. Which of the following antihypertensive agents in most likely to cause an exaggerated response to an injected catecholamine_____________?
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A. Hydralazine

B. Gauanethidine

C. A thiazide diuretic

D. Propranolol