9201. Which of the following can cause seizure ?
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A. Tacrolimus

B. Tramadol

C. Levocetrizine

D. Isoniazid
9204. In which of the following condition thalidomide may be used_______________?
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A. Erythema nodosum leprosum

B. Myocardial infarction

C. Epilepsy

D. Wernickes ecephalo pathy

9209. Which one is not converted to an active metabolite ?
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A. Fosinopril

B. Lisinopril

C. Quinapril

D. Benzopril

9210. Which of the following is used in the prophylaxis of migraine ?
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A. Carbamazepine

B. Phenobarbitone

C. Ethosuxamide

D. Topiramate
9211. Which antisialagogue is contraindicated in glaucoma_____________?
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A. Ephederine

B. Propranolone

C. Atropine

D. Morphine

9212. IV ultrashort acting barbiturate_____________?
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A. Phenobarbitone

B. Thiopentone

C. Meprobamate

D. Pentobarbitone

9213. Chloroxylenol has_______________?
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A. Local anesthetic property

B. Antibiotic action

C. Local anesthetic and antiseptic action

D. Antiseptic action
9214. Allergic reactions depends on all except____________?
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A. Pharmacological action of the drug

B. Antigen antibody reaction

C. previous exposure to the drug

D. Dosage of the drug received
9216. All of the following statements regarding biovailability of a drug are true except______________?
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A. Low oral biovailability always and necessarily mean poor absorption

B. It is the proportion (fraction) of unchanged drug that reaches the systemic circulation

C. Biovailability of an orally administered drug can be calculated by comparing the area under cure (o-a) after oral and intravenous (IV) administration

D. Biovailability can be determined from plasma concentration or urinary excretion data

9217. Which one of the following drugs is most commonly employed in an attack of angina pectoris ?
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A. Epinephrine

B. Sodium nitrate

C. Isosorbide dinitrate

D. Nitroglycerina
9219. Which of the following is not true about ACE inhibitors ?
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A. Postural hypotension is seen

B. Used in asthma

C. Na level decrease

D. Increase quality of life

9220. Relative contraindications for the administration of Ketamine hydrochioride include all of the following EXCEPT ?
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A. Age < 5 years

B. History of epilepsy

C. Recent anterior myocardial infarction

D. Raised intracranial tension

9221. Which factor of the following contributes to short duration of anesthetic action of single dose thiopental_____________?
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A. Rapid biotransformation

B. Ability to enter and leave brain tissue every rapidly

C. Rapid accumulation in body fat

D. High lipid solubility
9222. The principle central action of caffeine is on the________________?
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A. Spinal cord

B. Hypothalamus

C. Corpus callosum

D. Cerebral cortex
9223. Which of the following is not true for histamine ?
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A. Causes pain when injected subcutaneously

B. Causes arteriolar dialation

C. Is released following injury and in certain allergic responses

D. causes bronchodialtion
9225. Which of the following sympathominetic agents is the most bronchodilator_____________?
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A. Amphetamine

B. Isoproterenol

C. Phenylephrine

D. Nor epinephrine

9227. All of the following are vasodilators except______________?
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A. Procaine

B. Cyclopropane

C. Etomidate

D. Cocaine
9228. Drugs like barbiturates precipitate symptoms of prophyria because______________?
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A. They inhibit ALA synthase

B. They depress ALA synthase

C. They induce heme oxygenase

D. They inhibit heme oxygenase

9231. About articaine, all are true except_____________?
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A. More breaks down causes more toxicity

B. Mandibular infiltration is more effective than nerve block in mandibular molar teeth

C. Is amide which is metabolized in liver

D. Plasma half-life is 90 min
9234. Drug which causes gingival hyperplasia_____________?
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A. Nifedipine

B. Erythromycin

C. Cyclosporin

D. Aspirin

E. Both A & C
9235. Which one of the anti hypertensives is contraindicated in pregnancy ?
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A. Nifedipine

B. a-Methldopa

C. Enlapril

D. Hydralazine

9237. Blockers are used in all except_____________?
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A. Thyrotoxcosis

B. Phenochyromocytoma

C. Secondary shock

D. Migraine

9239. Teratogenicity is_______________?
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A. Drug dependence

B. Carcinoma forming tendency

C. Intolerance to a drug

D. Fetal malformation
9241. Heroin, an addict drug contains______________?
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A. Pentazocine

B. ASA

C. Acetyl morphine

D. Propoxyphene

9243. All of the following are predominant arteriolar dilators except____________?
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A. Nifedipine

B. Sodium Nitro prusside

C. Hydrallazine

D. Nitrates
9244. A prodrug is____________?
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A. The oldest member of a class of drugs

B. The proto type member of a class of drugs

C. A drug that is stored in body tissues and is then gradually released in the direction

D. An inactive drug that is transformed in the body to an active metabolite
9245. Toxic optic neuropathy can be caused by all of the following EXCEPT____________?
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A. Ethylene glycol

B. Tetracycline

C. Ethambutol

D. Ciprofloxacin
9246. Salicylate administration is contraindicated in pregnancy because_______________?
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A. Readily croses placental barrier

B. Causes pulmonary hypertension of newborn

C. It delay onset of labour

D. All of these
9248. Magnesium and Aluminium are added in Antacid because_____________?
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A. Mg Causes constipation, Al causes diarrhoea

B. Mg Causes Diarrhoea, Al Causes Constipation

C. Mg act as buffering agent and Al antagonize its action

D. Both increase gastric motility

9249. The most important property in determining the induction of a general anaesthetic agent is_____________?
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A. Alveolar exchage

B. Pulmonary ventilation

C. solubility of anaesthetic in tissue

D. Solubility of anaesthetic in blood