7351. Heart muscle, true are all except_______________?
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A. Act as syncytium

B. Has gap junctions

C. Has branching

D. Has multiple nuclei
7352. Effect on force of contraction of heart is_____________?
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A. Ionotropic effect

B. Chronotropic effect

C. Dromotropic effect

D. Bathmotropic

7353. All the heart valves are open during which stage of cardiac cycle __________________?
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A. Systolic ejection

B. None of the above

C. Isovolumetric relaxation

D. Isovolumetric contraction

7356. Inhibition of glycolysis by O2 is known a_____________?
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A. Gluconeogenesis

B. Pasteur effect

C. Hill reaction

D. Muni effect

7357. A example of a preventive antioxidant is_______________?
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A. Catalase

B. Superoxide dismutase

C. Tocopherol

D. Urate

7358. The main enzyme responsible for activation of xenobiotics in (detoxification)____________?
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A. Cytochrome P-450

B. NADPH cytochrome P-450 reductase

C. Glucuronyl transferase

D. Glutathione S-transferase

7359. In TCA, substrate level phospherylation takes place in______________?
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A. Alpha ketoglutrate to succinyl CoA

B. Oxalocetate to citrate

C. Succinate to fumarate

D. Succinyl CoA to Succinate
7361. Fructose intolerance is to_____________?
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A. Fructose and sucrose

B. Fructose and glucose

C. Fructose only

D. Sucrose only

7362. Sites where HMP shunts can occur include_______________?
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A. Lactating mammary gland

B. Liver

C. All of the above

D. WBC

E. Testes

7363. Enzymes stored in muscle is________________?
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A. SGPT

B. Alkaline phosphatase

C. CPK

D. SGOT

7364. The activity of this plasma enzyme is responsible virtually for all plasma cholesterol esters in humans_______________?
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A. Phospho mevalonate kinase

B. HMG CoA reductase

C. Lecithin cholesterol acyl transferase (LCAT)

D. Pyrophospho mevalonate decarboxylase

7366. The enzyme phosphofructo kinase-1 is strongly activated by_______________?
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A. Fructose 2,6 bis phosphate

B. Citrate

C. Adenosine tri phosphate

D. Cyclic AMP

7369. Ubiqultin is involved in_____________?
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A. Intracellular proteolysis

B. Electron transport chain

C. Transport of ATP

D. Protein folding

7370. Oligosaccharide is________________?
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A. Dextrin

B. Maltose

C. Gructose

D. Glucose

7371. Competitive enzyme inhibition will cause_____________?
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A. Decrease of km and increase of Vmax

B. Decrease of km and decrease of Vmax

C. Increase of km and Unchanged of Vmax

D. increase of km and increase of Vmax

7372. The end product of glycolysis under anaerobic conditions is_______________?
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A. Pyruvic acid

B. Acetoacetic acid

C. Oxaloacetic acid

D. Lactic acid
7375. Coenzyme responsible for single carbon transfer is______________?
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A. Acetyl co enzyme A

B. THF4

C. Pyridoxine

D. Biotin

7376. Which of the following statement is TRUE? The hydrolysis of lactose yields glucose and galactose_____________?
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A. The hydrolysis of lactose yields glucose and galactose

B. The hydrolysis of sucrose yields only glucose

C. The hydrolysis of maltose yields glucose and fructose

D. All of the above statements are true

7377. During conversion of glycerol to pyruvic acid, the first glycolytic intermediate to form is_______________?
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A. 2- phospho glyceric acid

B. Dihydroxy acetone phosphate

C. 3- phospho glyceric acid

D. 3- phospho glyceralehyde

7378. Krebs cycle does not occur in______________?
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A. RBC

B. All of the above

C. Muscle

D. Heart

7379. Glucose 6 phosphatase deficiency is seen in______________?
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A. McArdles syndrome

B. Downs syndrome

C. Von Gierkes disease

D. Pompers disease

7380. Enzymes concerned with the citric acid cycle are found in______________?
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A. Nucleus

B. Non-particulate cytoplasm

C. Mitochondria

D. Ribosomes

7381. Bile contains______________?
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A. All of the above

B. Lithocholic acid

C. Deoxycholic acid

D. Chenodeoxycholic acid

E. Cholic acid

7382. Muscle glycogen, which cannot contribute to blood glucose due to the absence of which enzymes ?
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A. Phosphoglutamase

B. Debranching enzyme

C. Branching enzyme

D. Glucose-6-phosphotase
7384. Serum alkaline phosphatase level increase in_______________?
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A. Hypothyroidism

B. Carcinoma of prostate

C. Hyperparathyroidism

D. Myocardial infarction

7385. Synthesis of protein occurs on_____________?
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A. Mitochondria

B. Poly ribosomes

C. Golgi bodies

D. Nucleus

7386. Multiienzyme complex in human_______________?
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A. Fatty acid synthetase

B. Malonyl CoA carboxylase

C. Carbomoyl Phosphate synthetase

D. Adenosine phospho ribosyl transferase

7387. Glucose can be synthesized from all except_____________?
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A. Glycerol

B. Acetoacetate

C. Lactic acid

D. Amino acids

7388. Which is not a oligosaccharide sugar ?
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A. Sucrose

B. Maltose

C. Lactose

D. Galactose
7390. Inactive precursors of enzymes are known as_______________?
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A. Coenzymes

B. Proenzymes

C. Holoenzymes

D. Apoenzymes

7391. Glycogen breakdown leads to formation of______________?
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A. Lactic acid

B. Glucose & Lactic acid

C. Glycoprotein

D. Glucose

7392. An enzyme not involved in glycolysis is______________?
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A. Phosphoglycero mutase

B. Aldolase

C. Glycerophosphate dehydrogenase

D. Enolase

7393. Which of them is multienzyme complex_____________?
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A. Pyruvate dehydrogenase

B. Alpha ketoglutarate dehydrogenase

C. Succinate dehydrogenase

D. Enolase

E. Both A & B
7395. The enzyme that is specifically increased in obstructive jaundice is_____________?
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A. Glutamate oxaloacetate transaminase

B. Alkaline phosphaase

C. Acid phosphatase

D. Glutamate pyruvate transaminase

7397. Which one of the following is the correct sequential order in which the given enzymes of krebs cycle are formed after a molecule of acetyl CoA______________?
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A. Citrate, Oxalocetate, Ketoglutarate

B. Citrate, Ketoglutarate, Oxalocetate

C. Oxalocetate, Ketoglutarate, Citrate

D. Ketoglutarate, Oxalocetate, Citrate

7398. Which of the following enzymes use NADP as coenzyme ________________?
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A. Lactate dehydrogenase

B. Beta hydroxy acyl CoA dehydrogenase

C. Glyceraldehyde 3 phosphate dehydrogenase

D. Glucose 6-Phosphate dehydrogenase
7399. Adrenaline acts on which enzyme in glycogenolysis ?
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A. Glucose diphosphatase

B. Hexokinase

C. Phosphorylase

D. Glucokinase

7400. Key glycolytic enzymes_____________?
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A. Phosphofructokinase

B. Glucose 1,6 diphosphatase

C. Pyruvate kinase

D. Hexokinase