1701. Somatic mutation of PTEN is seen in________________?
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A. Retinoblastoma

B. Endometrial Carcinoma

C. Carcinoma breast

D. Osteosarcoma

1702. The anticogulant of choice during pregnancy is______________?
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A. Heparin

B. Sodium oxalate

C. Warfarin sodium

D. Phenindone

1703. The first even in primary wound healing__________?
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A. Acute inflammatory response

B. Organization

C. Epithelial changes

D. Formation of blood cloth
1704. The most reliable post mortem features of left sided cardiac failure is____________?
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A. Enlargement of spleen and liver

B. Chronic venous congestion of lungs

C. Oedematous ankles

D. Systemic venous congestion

1705. Which of the following being is the most frequent site of thrombus ?
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A. Portal vein

B. Hepatic vein

C. Pulmonary vein

D. Veins of lower extremities
1706. Heparin, apart from releasing lypoprotein lipase in the blood exerts its anti-coagulant action by____________?
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A. Inhibiting prothrombin synthesis

B. Inhibiting thrombin synthesis

C. Binding to calcium

D. Inhibiting fibrinogen synthesis

1707. Why fetal cells continue to divide but terminally differentiated adult cells do not divide ?
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A. There are many cyclin inhibitors which prevent cell to enter into S phase in adult

B. Phosphatase absent in fetal cells

C. Proteinase is absent in fetus

D. Absence of CD kinase

1709. Which of the following has least capacity for regeneration_________________?
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A. All of the above

B. Cardiac muscle

C. Skeletal muscle

D. Neurons

1711. HOX gene is responsible for which malformation_____________?
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A. Polysyndactyly

B. Mayer Rokitansky syndrome

C. Gorlin syndrome

D. Holoprosencephaly

1713. Which of the following is correct?
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A. Internal jubular vein is direct continuation of sigmoid sinus

B. Subclavian vein is a continuation of axillarys vein

C. All of the above

D. Brahio cephalic vein is formed behind the sternoclavicular joint by the union of internal jugular vein and the sublavian vein

1715. All of the following drugs are non depolarizing neuromuscular blocking agents except_______________?
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A. D-tubocurarine

B. Succinylcholine

C. Pancuronium bromide

D. Gallamine triethiodide

1716. Anasarca means_____________?
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A. Abnormal inflammatory process

B. Presence of pus

C. Severe generalized swelling

D. Absence of proliferation of vessels following inflammation

1717. Transudate is characterized by__________?
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A. Low protein content

B. Tendency to clot

C. Associated inflammatory conditions

D. Specific gravity of above 1.018

1718. The persistence of epithelial cells after wound healing give rise to_______________?
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A. Implantation cyst

B. Keloid

C. Wound dehiscence

D. Cicatrisation

1719. Which of the following is not an action of epinephrine when administered intravenously in a high dose ?
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A. Increased liver glycogenolysis

B. Evokes extrasystoles in the heart

C. Causes broachiolar constriction

D. Produces restlessness and anxiety

1720. Onion skin appearance is seen in_______________?
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A. Ewings sarcoma

B. Osteosarcoma

C. Osteoma

D. Fibro sarcoma

1721. The wasting syndrome associated in cancer is_____________?
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A. Atelexis

B. Cacchexia

C. Cacoguesia

D. Achalasia

1722. Left side heart failure results in______________?
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A. Oedema of legs

B. Oedema of spleen

C. Oedema of lungs

D. Oedema of liver

1723. Which of the following is most common location of intracranial neurocysticercoses ?
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A. Medulla oblongata

B. Spinal card

C. Brain parenchyma

D. Basal cisternae

1724. Early positive reaction in lepromin test is___________?
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A. Wasserman reaction

B. Mituda reaction

C. Fernandez reaction

D. None of the above

1725. The increase in size of uterus during pregnancy is an example of ________________?
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A. Hyperplasia

B. Hypertrophy

C. Both of the above

D. None of the above

1726. Earliest lesion in atherosclerosis is_____________?
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A. None of the above

B. Fibrous plaque

C. Atheroma

D. Fatty streak
1728. Most tumours are ___________________?
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A. Multiclonal in origin

B. Biclonal in origin

C. Monoclonal in origin

D. None of the above

1729. Inflammation is characterized by________________?
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A. Exudation -> transudation -> oedema

B. Only by exudation -> oedema

C. Oedema -> exudation

D. Transudation -> exudation -> oedena
1731. Chronic inflammation is characterized by__________?
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A. Proliferation of fibroblasts and endothelial cells

B. Tissue

C. Presence of macrophages

D. All of the above
1733. Malignant tumour of skeletal muscie is__________________?
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A. Leiomyoma

B. Rhabdomyosarcoma

C. Rhabdomyoma

D. Leiomyosarcoma

1735. A person with glaucoma should not receive________________?
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A. Local anaesthetic

B. Sedatives

C. Vasoconstrictors

D. Antisialogogues
1736. Which of the following is not a mediator of inflammation___________?
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A. TNF

B. Prostaglandins

C. Interferon

D. Myeloperoxidase

1737. Malignant tumour of epithelial origin is_______________?
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A. Papilloma

B. Carcinoma

C. Sarcomas

D. All of the above

1738. Following is the most important factor in the management of shock_________________?
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A. CVP to 8 cm of water

B. Cardiac output

C. Blood pressure

D. Deficiency of effective circulating blood volume
1742. All of the following promotes wound healing except_________?
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A. Vitamin C

B. Adequate oxygen supply

C. Protein

D. Steroids
1744. In acute inflammation, immediate transient permeability in cells is increased by__________?
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A. Direct injury & necrosis

B. Increased tissue oncotic pressure

C. Endothelial Gaps by histamine

D. Leucocyte mediated endothelial injury

1745. The highest risk associated with use of oral contraceptives in________________?
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A. Permanent sterility

B. Thromboembolic disorders

C. Cancer of breast

D. Hepatic necrosis

1747. Ghon complex of the lung usually____________?
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A. Undergoes cavitation

B. Undergoes calcification

C. Progresses to tuberculous pneumonia

D. Progresses to military tuberculosis

1748. Which of the following predisposes to thrombogenesis ?
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A. Endothelial injury

B. Turbulence of blood

C. All of the above

D. Stasis of blood

1749. Bradykinin causes all the following except____________?
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A. Opsonisation

B. Pain

C. Smooth muscle contraction

D. Dilatation of blood vessels

1750. EBV causes all except_________________?
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A. Papilloma

B. Carcinoma of nasopharynx

C. Burkitts lymphoma

D. Infectious mononucleosis