1601. Down syndrome is caused by all except___________?
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A. Trisomy of 21 chromosome

B. Mosaicism of 21 chromosome

C. Robersonian translocation of 21.21, 21.18

D. Deletion of 21
1602. Infarcts are not common in______________?
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A. Liver

B. Lung

C. Kidney

D. Both A and B
1603. Fibrin degradation product help in detection of_______________?
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A. Thrombasthenia

B. DIC

C. haemophilia

D. Thrombocytopenic purpura

1604. Anaplasia is_______________?
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A. Is a characteristic feature of malignancy

B. Lack of structural differentiation

C. Lack of functional differentiation

D. All of the above
1605. Correct sequence of cell cycle ?
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A. Go G1 S G2 M

B. Go M G2 S G1

C. Go G1 S M G2

D. Go G1 G2 S M

1606. The commonest site of thrombosis is_______________?
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A. Heart

B. Arteries

C. Veins

D. Capilaries

1608. Granuloma is characterized by all of the following except______________?
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A. A specific type of chronic inflammation

B. Accumulation of modified macrophages

C. Initiated by a number of infectious and non infectious agents

D. A reaction of acute inflammation
1613. The factor which gives strength in wound healing_____________?
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A. Collagen

B. Growth factors

C. Hormones

D. Blood supply

1614. Function of hepatic kupffer cells is____________?
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A. Formation of sinusoids

B. Increases blood perfusion

C. Vitamin-A storage

D. Phagocytosis
1615. VIRCHOWs cells are seen in___________?
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A. Borderline lepromatous leprosy

B. Lepromatous leprosy

C. Tuberculoid leprosy

D. Intermediate leprosy

1616. Sunburst appearance and codmans triangle are seen in______________?
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A. None of the above

B. Osteoma

C. Chondrosarcoma

D. Osteosarcoma
1619. The characteristic feature of macrophage_____________?
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A. High capacity to divide

B. Limited capacity to divide

C. Long life span as compared to lymphocytes

D. Both B and C
1620. Dry mouth during antidepressant therapy is caused by blockade of______________?
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A. GABA receptors

B. Serotonergic receptors

C. Muscarinic acetylcholine receptors

D. Dopaminergic receptors

1621. A simple bacterial test for mutagenic carcinogens is________________?
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A. Bacteriophage

B. Redox text

C. Ames test

D. Gene splicing

1622. The type of embolism seen in fractures of long bones_____________?
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A. Fat embolism

B. Thrombo embolism

C. Air embolism

D. Amniotic fluid embolism

1624. Highly infection stage of syphilis______________?
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A. Congenital

B. Primary

C. Secondary

D. Tetriary

1628. Active hypermia is seen in_______________?
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A. All of the Above

B. Inflammation

C. Blushing

D. Muscles during exercise

1629. Primary hemostasis is disturbed in______________?
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A. Lupus anticoagulant

B. Hemophilia

C. Platelet disorder

D. Liver disease

1631. An acute inflammation would attract____________?
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A. Eosinophils

B. Plasma cells

C. Neutrophils

D. Monocytes

1632. Incomplete fractures of the bone are called___________?
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A. Simple fracture

B. Green stick fracture

C. Comminuted fracture

D. Compound fracture

1633. The common cause of sudden death in myocardial infarction is____________?
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A. Arrhythmias

B. None of the above

C. Pulmonary embolism

D. Congestive heart failure

1634. Which of the following is a vosoconstrictor______________?
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A. Bupivacaine

B. None of the above

C. Lidocaine

D. Procaine

1635. All of the following about prostaglandins and leukotriene are correct except________________?
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A. Leukotrienes cause bronchoconstriction

B. Arachidonic acid is metabolized to form prostaglandins and leukotrienes

C. COX-1 is inducible in many tissues

D. COX is induced by cytokines at the site of inflammation

1636. Identify the factors which decrease the effect of Oral anticoagulants_______________?
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A. Pregnancy

B. Nephrotic syndorme

C. Newborn

D. Liver disease

E. Both A & B
1638. Increased proliferation of cells is called_______________?
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A. Metaplasia

B. Atrophy

C. Hypertrophy

D. Hyperplasia
1639. Steroids________________?
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A. Exacerbate the inflammatory response

B. Steroids reduce the rate of repair of tissues thus delays the healing

C. Indicated in oral thrush

D. Can be safely given to immunocompromised patients

1640. Neoplasia of blood vessel is called______________?
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A. Papilloma

B. Lymphosarcoma

C. Hematoma

D. Angioma
1641. Virchow Lepra cells are seen in___________?
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A. Ideterminate leprosy

B. lepromatous leprosy

C. Tuberculoid leprosy

D. Borderline tuberculoid leprosy

1642. Edema occurs due to_____________?
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A. Decreased interstitial fluid

B. Increased capilary permeability

C. Decreased blood flow

D. Decreased capilary permeability

1643. Which of the following is correctly matched with the forms of extravasation hemorrhages______________?
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A. All of the above

B. petechiae small pin point hemorrhages

C. Ecchymosis large extravasation of blood in to the skin and mucous membrane

D. Purpura small areas (1cm) of hemorrhage in to the skin and mucous membrane

1645. Prostate specific antigen is used as____________?
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A. Proto oncogene

B. Bacterial antigen

C. Tumor marker

D. Oncogene

1646. Leucopenia is characteristic of____________?
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A. Appendicitis

B. Myocardial infarction

C. Enteric fever

D. Meningitis

1647. Immune response to tumour is mediated by_______________?
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A. All of the above

B. Cytotoxic T lymphocytes

C. Humoral mechanism

D. Natural killer cells

1649. The most characteristic feature of a neoplasm as opposed to inflammatory over growth is______________?
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A. Tendency to grow rapidly

B. Abnormal mitosis

C. Size of the lesion

D. Progressive growth after removal of causative stimuli