9751. Sunburst appearance and codmans triangle are seen in______________?
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A. Chondrosarcoma

B. Osteoma

C. None of the above

D. Osteosarcoma
9752. The following are recognized causes of neutropenia Except_______________?
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A. Aplastic anemia

B. Viral infection

C. Corticosteroid therapy

D. Typhoid fever

9753. All of the following statements are true regarding reversible cell injury, except______________?
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A. Diminished generation of adenosine triphosphate (ATP)

B. Detachment of ribosomes from the granular endoplasmic reticulum

C. Formation of amorphous densities in the mitochondrial matix

D. Formation of blebs in the plasma membrane

9754. T-Helper cells (TH2) initiates which type of immunity_______________?
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A. Induces cell mediated immunity

B. None of the above

C. Induces Humoral immunity

D. Induces immunity by activation of cytoxic T-cells

9755. All of the following vascular changes are observed in acute inflammation except_____________?
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A. Increased vascular permeability

B. Stasis of blood

C. Vasodilation

D. Decreased hydrostatic pressure
9759. The wasting syndrome associated in cancer is_____________?
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A. Atelexis

B. Achalasia

C. Cacchexia

D. Cacoguesia

9760. Which of the following is correctly matched with the forms of extravasation hemorrhages______________?
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A. petechiae small pin point hemorrhages

B. Ecchymosis large extravasation of blood in to the skin and mucous membrane

C. Purpura small areas (1cm) of hemorrhage in to the skin and mucous membrane

D. All of the above
9761. In sickle cell anaemia there is_____________?
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A. 75 to 100% haemoglobins

B. 20 to 30% haemoglobins

C. 10 to 20% haemoglobins

D. 50 to 60% haemoglobins

9762. Hodgkins lymphoma can be distinguished from non Hodgkins lymphomas by_________________?
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A. Systemic manifestations

B. All of the above

C. Reed Sternberg cells

D. Occurence in young adults

9765. Disappearance of nuclear chromatin is called as__________?
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A. None

B. Karyorhexis

C. Pyknosis

D. Karyolysis
9766. Syndrome which is characterized by 2X chromosomes and 1Y chromosome is_____________?
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A. Turner syndrome

B. Down syndrome

C. Kleinfelters syndrome

D. Marfan syndrome

9767. Tissue macrophages are called__________?
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A. Kupffer cells in liver

B. Histiocytes in connective tissues

C. All of the above

D. Microglial cells in nervous system

9768. Endotoxic shock is propagated____________?
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A. Peripheral vasodilation

B. Cytokine action

C. Increased vascular permeability

D. Endothelial injury

9769. Which of the following statement about fibrinous exudate is FALSE ?
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A. It has fibrin precipitates

B. It is associated with many types of severe inflammation

C. It has low protein content

D. It induces connective tissue organization

9771. Which one of the following does not present antigens ?
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A. Macrophages

B. Dendritic cells

C. Langerhans cells

D. NK cells (Netural killer cells)
9772. Pap smear is used to detect dysplasia, carcinoma insitu and invasive carcinoma of uterine cervix. This is based on the principle of_______________?
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A. Neoplastic cells are are non cohesive

B. Hyper chromatic and pleomorphism of tumour cells

C. All of the above

D. Neoplastic cells are cohesive

9773. Which of the following is not present in lungs ?
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A. Klutischky cells

B. Brush cells

C. Clara cells

D. Langerhans cells
9774. Which is associated with defect in DNA repair___________?
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A. Sickle cell anaemia

B. Albinism

C. Icthyosis

D. Xeroderma pigmentosum
9775. Malignant tumour of epithelial origin is_______________?
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A. All of the above

B. Papilloma

C. Sarcomas

D. Carcinoma
9777. Carcinogens induce tumours, they are________________?
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A. All of the above

B. Chemicals

C. Viruses

D. Radiation

9778. Serum sickness syndrome is_____________?
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A. None of the above

B. A transplant immunity

C. An anaphylactic shock

D. Systemic arthus reaction
9779. Major and frequent influence for thrombus formation is________________?
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A. Fatty streak

B. Hypercoagulability

C. Alteration in blood flow

D. Endothelial damage
9780. Increased levels of haemoglobin A2 is characteristic of________________?
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A. Glucose-6 phosphate dehydrogenase deficiency

B. Sickle cell trait

C. b-thalassaemia crait

D. a-Thalassamia

9781. Nevus cell are_______________?
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A. Modified melanocytes

B. Cells containing excessive melanin pigment

C. Melangocytes which are functionally more active

D. large melanocytes

9782. Which of the following is correct statement ?
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A. TNM and AJC systems can be used for staging malignant tumours

B. Staging is the extent of spread of tumour

C. Grading is the degree of macroscopic and microscopic differentiation of tumour

D. All of the above
9783. Difference in transudate & exudate is that the former has a______________?
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A. Cloudy appearance

B. Low protein

C. Increased specific gravity

D. High protein

9784. Edema is due to_______________?
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A. Decreased albumin conc. in blood

B. Increased osmotic pressure

C. Increased albumin in blood and decreased globin

D. None of the above

9785. Metastatic calcifications are seen in______________?
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A. Hypoparathyroidism

B. Vitamin D deficiency

C. All of the above

D. Hypercalcemia
9786. Christmas disease is due to deficiency of________________?
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A. Factor VIII

B. Factor X

C. Factor IX

D. Factor V

9788. Severe generalized edema is called as_______________?
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A. Myxoedema

B. Anasarca

C. Dependent edema

D. Pitting edema

9789. Which of the following is NOT true of dystrophic calcification ?
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A. Tuberculous lesions

B. Atherosclerotic lesions

C. Occurs in damaged tissue

D. Serum calcium levels are high
9790. Pallor, spoon shaped nails, atrophic glossitis, with accompanied dysphagia is typical picture of ______________?
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A. Trotters syndrome

B. Vincent stomatitis

C. None of the above

D. Plummer Vinson syndrome
9791. In Hodgkins disease the lymphoa cells seen are__________________?
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A. Giant cells

B. Plasma cells

C. Reed-sternberg cells

D. Eosinophilis

9793. The activation of caspases is likely to lead to_________________?
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A. G1 to S phase of cell cycle

B. Blood coagulation

C. Apoptotic cell death

D. Mitotic cell division

9794. Chicken-wire appearance of enlarged bone marrow spaces is seen in_______________?
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A. Haemophilia A

B. Sickle cell anaemia

C. Beta thalassemia majon

D. Fetal alcohol syndrome

9795. Caseation necrosis is suggestive of________________?
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A. Sarcoidosis

B. Leprosy

C. Tuberculosis

D. Midline lethal granuloma

9796. Coagulative necrosis is_______________?
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A. Characteristic of focal bacterial infections

B. Characteristic by loss of tissue architecture

C. Characteristic of hypoxic death

D. None of the above

9797. Diabetic gangrene is caused by____________?
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A. Vasospasm

B. Peripheral neuritis

C. Atheroslerosis

D. None of the above

9798. Hyper segmented neutrophils are seen in_________________?
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A. Iron deficiency anemia

B. Idiopathic thrombocytopenic purpura

C. Megaloblastic anemia

D. Thalassemia

9799. Stain used for demonstration of amyloid is______________?
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A. Congo Red

B. Massons toichrome

C. Reticulin

D. Vonkosa

9800. Hemophilia is best treated by _____________?
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A. Whole blood

B. cryoprecipitate

C. factor VIII concentrate

D. dried freeze plasma