7501. Mutation in the oxidative enzymes (peroxisomes) could lead to_______________?
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A. Lebers neuropathy

B. Zellwegers syndrome

C. Gauchers disease

D. Epidermolysis bullosa

7502. Type II glycogen storage disorder is due to deficiency of______________?
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A. Alpha galactosidase

B. Alpha -Glucosidase

C. Muscle phosphorylase

D. Acid Lipase

7503. The uptake of glucose by the liver increase following a carbohydrate meal because____________?
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A. GLUT-2 stimulated by insulin

B. Glucokinase has a low Km for glucose

C. There is increase in phosphorylation of glucose by glucokinase

D. Hexokinase in liver has a high affinity for glucose

7504. Phosphofructokinase is the key enzyme of______________?
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A. Gluconeogenesis

B. Glycolysis

C. Beta oxidation

D. TCA cycle

7507. Which of the following is not a second messenger ?
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A. c GMP

B. Phosphatidyl glycerol

C. Phosphatidyl inosital

D. c AMP

7509. Cane sugar is____________?
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A. Surose

B. Glucose

C. Fructose

D. Maltose

7510. Kinase requires_______________?
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A. Inorganic phosphate

B. Mg++

C. Cu++

D. MN++

7512. Urea is formed in_____________?
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A. Liver

B. Brain

C. Kidney

D. Intestine

7513. Acetyl CoA is produced from which fuel sources_____________?
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A. Amino acids

B. Carbohydrate

C. All of the above

D. Lipid

7514. Sources of the nucleotide portion of NAD include__________________?
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A. Tryptophan

B. N-methyl nicotinamide

C. Riboflavin

D. PRPP

7516. On complete hydrolysis of DNA we will get all the following except______________?
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A. Deoxy pentose sugar

B. Phosphoric acid

C. Purine bases

D. Adenosine
7517. Major source of ammonia in the kidney is___________?
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A. Aspartate

B. Glutamate

C. Glutamine

D. Urea Aspartate

7518. Vitamin C effects_________________?
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A. Maturation of procollagen

B. Formation of osteoid matrix

C. Calcification of osteoid

D. Both A and B
7520. The major lipids that make up the cell membrane are_______________?
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A. Triglycerides

B. Phospholipids

C. Fatty acids

D. Sphingomyelins

7521. In Hartnups disease _______ is excreted in the urine?
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A. Phenylalanine

B. Tryptophan

C. Ornithine

D. Glutamine

7522. The amino acid from which niacin synthesized is_______________?
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A. Threonine

B. Tryptophan

C. Tyrosine

D. Histidine

7523. The precursor of cholesterol synthesis is________________?
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A. Pyruvate

B. Acetyl CoA

C. Oxalo acetic acid

D. Acetic acid

7524. Ascorbic acid_____________?
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A. Is requirement for lysyl oxidase

B. Is harmless in high doses

C. Is a reducing agent

D. Decrease iron absorption

7525. Proteins are absorbed from GIT as_____________?
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A. Amino acids

B. All of the above

C. Peptides

D. Peptones

7526. Key enzyme in urea synthesis is____________?
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A. Arginase

B. Ornithine

C. Carbamyl synthetase

D. Urease

7527. Pernicious anaemia occurs in___________?
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A. Vit C deficiency

B. Vit D deficiency

C. Vit B1 deficiency

D. Vit B12 deficiency
7528. Which of the following is not a ketone body______________?
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A. Acetocetate

B. Acetone

C. Acetic acid

D. Beta hydroxybutyric acid

7529. Xerophthalmia is caused by_______________?
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A. Vitamin K deficiency

B. Vitamin D deficiency

C. Vitamin A deficiency

D. Vitamin C deficiency

7532. All are derived of cholesterol except________________?
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A. Glycocholic acid

B. Cholecystokinin

C. Chenodeoxy cholic acid

D. Testosterone

7533. Lipid is required in the average diet because it________________?
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A. is necessary for storage of carbohydrates

B. Provides essential fatty acid

C. aids in absorption of carbohydrates

D. has a high caloric value

7534. B-oxidation of odd-chain fatty aids produce_______________?
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A. Propionyl CoA

B. Acetyl CoA

C. Succinyl CoA

D. Malonyl CoA

7535. Aniacinosis results in______________?
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A. Beri beri

B. Perleche

C. Nyctalopia

D. Pellagra
7536. The precursor of steroid is_______________?
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A. Cholesterol

B. None of the above

C. Amino acids

D. Fatty acids

7537. All are genetic amino acid deficiency disease except___________?
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A. 6alactosemia

B. Alkaptonuria

C. Homocystinuria

D. Phenyl ketonuria

7538. Which of the following fatty acids are not syntehsised in human body_____________?
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A. Linoleic, arachidonic and stearic acid

B. Oleic, linoleic and linolenic acid

C. Arachidonic, linolenic and linoleic acid

D. Palmitic Oleic and arachidonic

7540. Histidine is converted to histamine by_____________?
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A. Transamination

B. Hydroxylation

C. Reduction

D. Decarboxylation
7541. Detoxification of drugs is controlled by_____________?
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A. Cytochrome P450

B. Cytochrome A

C. Cytochrome

D. Cytochrome C

7542. The major fuel for the brain after several weeds of starvation______________?
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A. Glucose

B. Fatty acid

C. Beta hydroxy butyrate

D. Glycerol

7544. Examples of monounsaturted fatty acids are______________?
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A. Linolenic acid

B. Oleic acid

C. Palmitic acid

D. Arachitlonic acid

7545. Indole ring is present in______________?
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A. Tryptophan

B. Methionine

C. Valine

D. Histidine

7546. Iron absorption is decreased in presence of all except____________?
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A. Phosphates

B. Ascorbic acid

C. Tannins

D. Phytates

7547. Chargaff rule states that___________?
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A. A+G=T+C

B. A+T=G+C

C. A/T=G/C

D. A=U=T=G=C

7549. The following is false about tryptophan_____________?
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A. Non-essential amino acid

B. Involved in serotonin synthesis

C. Involved in melatonin in synthesis

D. Involved in niacin synthesis

7550. The normal range of serum osmolality (in mosm/L) is_____________?
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A. 350 to 375

B. 300 to 320

C. 280 to 295

D. 200 to 250