1153. Drug which causes gingival hyperplasia_____________?
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A. Nifedipine

B. Erythromycin

C. Cyclosporin

D. Aspirin

E. Both A & C
1155. Lidocaine produces its antiarrhythmic effects by_____________?
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A. Decreasing cardiac excitability

B. Increasing cardiac conduction velocity

C. Increasing spontaneous pacemaker activity

D. Increasing A-V conduction

1157. Relative contraindications for the administration of Ketamine hydrochioride include all of the following EXCEPT ?
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A. History of epilepsy

B. Raised intracranial tension

C. Recent anterior myocardial infarction

D. Age < 5 years

1158. What is the advantage of sublingual route of administration of drugs_____________?
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A. Can be spitted out with signs of toxicity

B. prevents or bypasses first pass effects

C. Easy to administer

D. Lipid soluble

1160. All of the following drugs cause dryness of mouth except_______________?
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A. Neostigmine

B. Atropine

C. Imipramine

D. Chlorpheniramine

1161. An attack of bronchial asthma is most likely to be triggered by________________?
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A. Aspirin

B. Ibuprufen

C. Diclofenac potassium

D. Mefenamic acid

E. Both A & B
1163. The ratio of the median lethal dose of the median effective dose is the_____________?
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A. Moratality index

B. Anesthetic ratio

C. Morbidity index

D. Therapeutic index
1164. Which of the following is true about parasympathetic nervous system ?
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A. Ach is transmitter at both pre & post synaptic junction

B. It causes dilatation of skeletal muscles

C. Post ganglionic fibres are longer than pre ganglionic fibres

D. Noradrenalin is the neurotransmitter at post ganglionic junction

1166. Potassium permanganate is used for_______________?
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A. Cleaning surgical instruments

B. Irrigating cavities

C. Dinisfect water in wells

D. Gargling

1167. Progestin compound that does not alter lipid profile is______________?
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A. Levonorgestrel

B. Norethindrone

C. Medroxyprogesterone

D. Gestodene
1171. All of the following are predominant arteriolar dilators except____________?
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A. Hydrallazine

B. Sodium Nitro prusside

C. Nitrates

D. Nifedipine

1172. The drug combination which produces Neuroleptanalgesia is______________?
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A. Daroperidol + Fentanyl

B. Droperiodl + Thiopental sodium + Nitrous oxide

C. Deroperidol + Ketamine

D. Droperiodl + Ether

1173. Morphine is contraindicated in all of the following except_______________?
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A. Head injury

B. Emphysema

C. Pulmonary oedema

D. Bronchial asthma

1174. The most common type of epilepsy in children is________________?
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A. Petit mal

B. None of the above

C. Grand mal epilepsy

D. Infantile spasm

1175. Antagonist of morphine is_______________?
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A. Nalpuphine

B. Methadine

C. Nalosphine

D. Naloxone
1176. Which of the following drugs will not produce allergic reactions ?
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A. Certrizine

B. Pencillins

C. Sulfonamides

D. Cephalosporins

1178. All of the following are tocolytic except_______________?
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A. Natrexam

B. Atosiban

C. Isoxsuprine

D. Ritodrine

1179. In the second stage of anesthesia the pupil is_______________?
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A. Partially dilated

B. Normal in size

C. Totally dilated

D. Constricted

1182. A patient on digoxin should not be given quindine because______________?
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A. Displaces digoxin from its protein binding sites

B. Decrease the renal clearance of digoxin

C. Displaces digoxine from its tissue binding sites

D. Decreases the plasma potassium level

1183. Allergic reactions depends on all except____________?
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A. Dosage of the drug received

B. previous exposure to the drug

C. Antigen antibody reaction

D. Pharmacological action of the drug

1184. Atypical Antipsychotic are all except______________?
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A. Clozapine

B. Thioridazone

C. Olanzepine

D. Risperidone

1186. Drug injury may be caused by therapeutic drugs or______________?
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A. All of the above

B. Allergens

C. Nontherapeutic agents

D. Carcinogens

1187. Drugs showing zero order kinetics of elimination_____________?
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A. Are more common than first order kinetics

B. Show a plot of drug concentration versus time that is linear

C. Have a half life independent of dose

D. Decrease in concentration exponentially with time

1188. Which of the following is a leukotriene antagonist ?
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A. Zileuton

B. Montelukast

C. Nedocromil

D. Misopristol

1189. Naturally occurring local anaesthetic________________?
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A. None of the above

B. Lignocaine

C. Cocaine

D. Procaine

1190. All of the following statements about pain are correct except_____________?
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A. Naloxane is a non-competitive antagonist and irreversibly opposes the opioids

B. Analgesia is associated with ? and k receptors

C. NSAIDS benefit by preventing prostaglandin synthesis

D. Dysphoria is associated with S receptors

1191. Verrils sign is seen in_________________?
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A. Digitalis toxicity

B. Diazepam administration

C. Pagets disease

D. Unconscious states

1193. All of the following are true except____________?
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A. A special application of dantrolene is used to treat malignant hyperthermia

B. Thalidomide is used for the treatment of leprosy

C. Allopurinol is a derivative of 8-mercaptopurine

D. Interferons have a role in immunology of cancer

1194. INFLIXIMAB (systemic) is used in_____________?
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A. Rheumatoid arthritis (treatment)

B. All of the above

C. To reduce the number of draining enterocutaneous fistula(s) in patients with fistulizing crohns disease

D. Crohns disease (treatment)

1195. Finasteride is a ?
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A. 5 alpha reductase inhibitor

B. PDE inhibitor

C. Androgen receptor blocker

D. Alpha blocker

1196. A drug A & B compared, all are true except____________?
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A. 1 mg of A cause effect not caused by 1 mg of B so A is more efficacious

B. 1 mg of A causes same effect of 3 mg of B, so A is more potent

C. Efficacy is not dose dependent

D. 1 mg of A cause effect not even caused by maximum tolerated dose of B, so drug A is more efficacious

1197. Which of the following is a mismatch ?
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A. Naloxone-Tricyclic antidepressant

B. Acetaminophen anti inflammatory

C. Herbicide and earth materials allergies

D. Warfarin- Oral anticoagulant

1198. American society of anesthesiologists physical status classification system, P2 is a is a patient who______________?
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A. With severe systemic disease

B. Is healthy

C. With mild systemic disease

D. None of the above

1199. Combination of ampicillin and gentamicin is an example of_____________?
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A. Synergy

B. Indifference

C. Bacterial symbiosis

D. Antagonism

1200. When a drug creates an effect that is unpredictable and unique it is termed as____________?
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A. Side effect

B. Idiosyncratic effect

C. Drug on Drug effect

D. Toxicity effect