1251. Clavulanic acid is given in combination with amoxicillin in order to____________?
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A. Reduce the risk allergic reactions:

B. Reduce the severity of diarrhea

C. Extend amoxicillins antibacterial spectrum

D. Prolong amoxicillins half-life

1252. Cephalosporin active against pseudomonas aeruginosa______________?
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A. Cefaclor

B. Ceftriaxone

C. Cefotaxime

D. Cefoperazone
1253. All of the following are endogenous corticosteriods released by all adrenal cortex EXCEPT______________?
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A. Cortisol

B. Aldosterone

C. Cortisone

D. Dexamethsone
1254. About heparin true is_____________?
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A. Decrease action of prothrombin III

B. Known to cause idiopathic thrombocytosis

C. Mixture of sulphated polypeptide

D. Half-life is 90 min
1255. Which of the following combination of iron can be given both IM and IV____________?
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A. ferrous Humourate

B. Iron Sorbitol Citrate Solution

C. ferrous Sulphate

D. Iron dextran
1256. Cyclosporin is used an______________?
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A. Antibiotic

B. Immunosuppresant

C. Antiarrythmic

D. Anticancer drug

1257. Which of the following drugs is used to treat both diabetes mellitus and diabetes insipidus_____________?
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A. Glipizide

B. Glibenclamide

C. Chlorpropamide

D. Glicazide

1258. The mechanism of action of sodium nitroprusside is_____________?
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A. Direct Vasodilator

B. Increases cAMP

C. Block the sympathetic flow at hypothalamus

D. Calcium channel blocker

1259. The most serious side effect of drug chloramp henicol is______________?
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A. Bone marrow depression

B. Candidiasis

C. Photosensitivity

D. Angioneurotic oedema

1260. Which of the following antibiotics is most frequently associated with pseudomembranous colitis ?
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A. Ampicillin

B. Clindamycin

C. Cephalosporin

D. Penicillin

1261. Which one of the anti hypertensives is contraindicated in pregnancy ?
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A. Enlapril

B. Hydralazine

C. Nifedipine

D. a-Methldopa

1262. A patient taking which of the following drug should not eat cheese, etc_____________?
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A. Triamterene

B. Tetracycline

C. Amoxycillin

D. Doxycycline

1263. Roxithromycin is______________?
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A. Long acting polypeptide

B. Short action quinolone

C. Short acting macrolide

D. A long acting macrolide
1264. Which of the following antibiotics is found at much higher concentrations in cervicular fluid than in serum ?
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A. Tetracyline

B. Clindamycin

C. Penicillin

D. Metronidazole

1265. Omeprazole is a_____________?
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A. Ulcer healing drug

B. Antihistamine

C. Proton pump inhibitor

D. Ulcer protective

1266. One of the drug is betalactamase inhibitor_____________?
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A. Pencillin G

B. Ampicillin

C. Cloxacillin

D. Sulbactum
1267. Which on of the following is penicillinase resistant penicillin_______________?
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A. Penicillin G

B. Cloxacillin

C. Amoxycillin

D. Ampicillin

1268. Agents/Drugs which help in rapid coagulation of Blood_______________?
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A. Haemostatics

B. Astrigents

C. Styptics

D. All of the above
1269. Scopolamine helps in________________?
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A. Decreased secretions

B. Hypertension

C. Motion sickness

D. A & C
1270. Which of the following is an ACE inhibitor ?
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A. Diltiazem

B. Coptopril

C. Spirino lactone

D. Saralosin

1271. Tetracycline in children causes____________?
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A. Discolored teeth

B. Calcification

C. Missing teeth

D. Peg teeth

1272. Desfuroxamide is a drug used for____________?
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A. Pain control

B. Pernicious anaemia

C. Kala azar

D. Thalassemia
1273. All of the following are true about tolbutamide except____________?
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A. It acts on pancreas to stimulate release of insulin

B. It is taken orally

C. It causes alcohol intolerance

D. It is used in type-I diabetes mellitus
1274. Traces of which of the antibiotics can be found in the gingival fluid after administration___________?
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A. Clindamyclin

B. Tetracycline

C. Lincomycin

D. Penicillin G

1275. Hypokalemia is seen in therapy with____________?
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A. Corticosteroids

B. Ibuprufen

C. Diazepam

D. Digitalis
1276. Which of the following is not caused by Frusemide____________?
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A. Hyperuricemia

B. Hyponatremia

C. Hypokalemia

D. Hypercalcemia
1277. Mechanism of action of nifidipine is_____________?
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A. Mainly depression of A-V conduction

B. Nifidipine depresses the SA node thus decreasing mycocoardial excitability

C. It has a prominent smooth muscle relaxant action causes arteolar dilation leading to fall in blood pressure

D. Decreased cardiac output thus decreasing load on myocardium

1278. All of the following drugs are primarily bacteriostatic except______________?
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A. Sulphonamide

B. Rifampin

C. Chloramphenicol

D. Ethambutol

1279. Topical Antifungal agent in candidiasis is______________?
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A. Ornidazole

B. Propronolol

C. Clotrimazole

D. Clotrimoxazole

1280. Drug to be avoided in a patient allergic to penicillin is_____________?
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A. Ampicillin

B. Sulphonamide

C. Tetracycline

D. Cholarmphenicol

1281. Optic neuritis is a side effect of______________?
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A. Pyrazinamide

B. Rifampicin

C. INH

D. Ethambutol
1282. Which of the following is not an antimigraine agent ?
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A. Flunarizine

B. Zonisamide

C. Divalprox sodium

D. Propanolol

1283. Penicillin is effective against_____________?
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A. Neisseria gonorrhoeae

B. Neisseria meningitis

C. Treponema Pallidum

D. All of the above
1284. All of the following drugs are contraindicated in patients with G-6-PD deficiency, except____________?
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A. Nalidixic acid

B. Furazolidone

C. Cotrimoxazole

D. Ceftriaxone
1285. The group of antibiotics which possess additional anti-inflammatory and immunomodulatory activities is_____________?
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A. Fluoroquinolones

B. Polypeptide antibiotics

C. Tetracyclines

D. Macrolides
1286. Which anti tubercullar drug will cause transjent memory loss ?
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A. INH

B. Pyrazinamide

C. Ethambutol

D. Enthionamide

1287. Following inhibits Cytochrome P450_____________?
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A. Ranitidine

B. Cimetidine

C. Famotidine

D. All of the above

1288. Cephalosporines have all of the following interactions except_____________?
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A. Are used in upper respiratory tract infections

B. Are penicillinase resistant

C. Show cross sensitivity with penicillins

D. Have a broad spectrum but are inactive against anaerobes

1289. Mechanism of action of chlortetracycline_____________?
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A. Inhibition of cell wall formation

B. Inhibition of protein synthesis

C. Interfere with metabolism

D. Interfere with DNA function

1290. Mode of action of sulphonyl ureas includes all the following except______________?
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A. Inhibiting gluconeogenesis in liver

B. Enhancing insulin mediated post receptor enzyme reaction

C. Decreasing Glucose absorption from the qut

D. Activating receptors on beta cells of pancreas to release insulin

1291. Combination chemotherapy is used in tuberculosis in order to reduce____________?
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A. Side effects of drugs

B. Development of drug resistance

C. Dosage of drugs

D. Cost of therapy

1292. Which of the following is a characteristic of tetracycline stains ?
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A. Is always accompanied by hypolastic defects

B. Stained teeth fluoresce light yellow under U.V light

C. Stains are dark brown in color

D. There is less deposition in dentine as compared to enamel

1293. Which of the following is a peripherally acting muscle relaxant______________?
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A. Chlorozoxazone

B. Cortisopradol

C. Methocarbomol

D. Succinyl choline
1294. Which one is not converted to an active metabolite ?
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A. Fosinopril

B. Quinapril

C. Benzopril

D. Lisinopril
1295. Drug chemically related to penicillins is_____________?
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A. Cephalosporin

B. Sulphonamide

C. Tetracycline

D. Lincemycin

1296. Adrenaline is used in following EXCEPT______________?
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A. With xylocaine

B. Post extraction socket

C. Anaphylactin shock

D. Angina in dental chair

E. Both B & D
1297. Which of the following is not true about ACE inhibitors ?
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A. Used in asthma

B. Postural hypotension is seen

C. Na level decrease

D. Increase quality of life

1298. Succinylcholine is a/an______________?
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A. Short-acting narcotic

B. None of the above

C. Intravenous anaesthetic agent

D. Non-depolarizing muscle relaxant

1299. Among the drugs given below, which is LEAST likely to be implicated in drug induced hepatitis ?
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A. Pyrazinamide

B. Streptomycin

C. Isoniazid

D. Ripampicin

1300. IF a bacteria were susceptible to both penicillin and Erythromycin, then it would not be appropriate to treat the patients with both antibiotics at the same time because_______________?
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A. Erythromycin enhances the B-lactamases activity

B. Penicillin is only effective against growing cells

C. Penicillin is inactivated by erythromycin

D. Erythromycin exerts its effects extracellularly