9501. Which of the following drugs undergoes Hoffmann elimination ?
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A. d-tubecurarine

B. Acetazolamide

C. Atracurium

D. Acetycholine

9502. Drugs producing ototoxicity and Nephro toxicity are______________?
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A. Macrolides

B. Tetracyclines

C. Quinalones

D. Aminoglycosides
9503. Granesetron, the antiemetic properties because of____________?
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A. Gaba-inhibitory actions

B. Dopaminergic receptor blocking actions

C. Gabamimetic actions

D. Serotonin receptor blocking action
9504. The drug of choice in the management of life threatening allergic reaction is______________?
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A. Diazepam

B. Corticosteroids

C. Antihistamines

D. Adrenalin
9505. The oral microblal fiora of a patient on prolonged broad spectrume antibiotic therapy is predominantly____________?
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A. Anaerobic

B. Gram positive organism

C. Gram negative organisms

D. Yeast and fungi
9506. Which antibiotic is effective against pseudomonas and indole +ve proteus ?
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A. Oxacillin

B. Lincomycin

C. Methicillin

D. Carbenicillin
9507. In treating Xerostomia, Which of the following might be prescribed ?
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A. Atropine

B. Scopalamine

C. Neostigmine

D. Ephedrine

9508. Identify the factors which decrease the effect of Oral anticoagulants_______________?
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A. Pregnancy

B. Nephrotic syndorme

C. Newborn

D. Liver disease

E. Both A & B
9509. Drugs causing hyperglycemia_______________?
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A. Glucocorticoids

B. a-blockers

C. Acetylcholine

D. B-blocker

9510. Dry mouth during antidepressant therapy is caused by blockade of______________?
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A. Dopaminergic receptors

B. Serotonergic receptors

C. Muscarinic acetylcholine receptors

D. GABA receptors

9511. The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is___________?
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A. Penicilling G

B. Ampicillin

C. Erythromycin

D. Methicillin sodium

9512. Desfuroxamide is a drug used for____________?
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A. Kala azar

B. Pernicious anaemia

C. Pain control

D. Thalassemia
9513. The drug which is used to treat laryngospasm is_______________?
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A. Atropine

B. Neostigmine

C. Diazepam

D. Succinylcholine
9514. Mode of action of sulphonyl ureas includes all the following except______________?
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A. Decreasing Glucose absorption from the qut

B. Inhibiting gluconeogenesis in liver

C. Activating receptors on beta cells of pancreas to release insulin

D. Enhancing insulin mediated post receptor enzyme reaction

9515. Oral infection by penicillinase producing organisms should be treated with____________?
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A. Ampicillin

B. Dicloxacillin

C. Erythromycin

D. Any of the above

9516. The antibiotic of choice in patients sensitive to penicillin is___________?
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A. Tetracycline

B. Chloramphenicol

C. Erythromycin

D. Streptomycin

9517. Tetracycline in children causes____________?
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A. Peg teeth

B. Calcification

C. Discolored teeth

D. Missing teeth

9518. The intramuscular administration of 0.6 mg of atropine sulphate to a 50 kg adult may produce all of the following effects except_____________?
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A. Bradycardia

B. Decreased Sweating

C. Mydriasis

D. Decreased Salivation

9519. The therapeutic advantage that pencillin V has over pencillin G is____________?
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A. Greater resistance to pencillinase

B. More reliable oral obsorption

C. Broader antibacterial spectrum

D. Slower renal excretion

9520. Which of the following penicillins is given by oral route ?
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A. Benzathine penicillin

B. Procaine pencillin

C. Penicillin V / Phenoxymethyl penicillin

D. Benzyl penicillin

9521. True about aminoglycoside is all except______________?
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A. Excreted unchanged in urine

B. Teratogenic

C. Are bacteriostatic

D. Distributed only extracellularly

9522. Which of the following is beta-lactam antibiotic ?
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A. Carbamide

B. Sulphonamide

C. Ofloxacin

D. Cephalosporins
9523. Short-acting non-depolarising muscle relaxant is________________?
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A. Succinylcholine

B. Decamethonium

C. Pancuronium

D. Mivacurum
9524. Which drug can be safely used in lactating mothers ?
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A. Ampicillin

B. Erythromycin

C. Ciprofloxacin

D. Chloramphenicol

9525. Succinylcholine prevents bronchospasm by______________?
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A. Centrally acting muscle relaxation

B. Dual action

C. Direct muscle relaxation

D. Depolarising block
9526. Indirect sympathomimetics can_______________?
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A. Penetrate the blood brain barrier

B. Cause euphoria

C. Both of the above

D. None of the above

9527. All are true about nitric oxide, EXCEPT____________?
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A. Present in cigarette smoke

B. Acts via cAMP

C. Regulates vasomotor tone

D. It is important in penile erection

9528. Drug to be avoided in a patient allergic to penicillin is_____________?
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A. Sulphonamide

B. Ampicillin

C. Tetracycline

D. Cholarmphenicol

9529. Mechanism of action of nifidipine is_____________?
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A. It has a prominent smooth muscle relaxant action causes arteolar dilation leading to fall in blood pressure

B. Decreased cardiac output thus decreasing load on myocardium

C. Nifidipine depresses the SA node thus decreasing mycocoardial excitability

D. Mainly depression of A-V conduction

9530. Which of the following antibiotics is not used in the treatment of infectious mononucleosis ?
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A. Ampicillin

B. Gentamycin

C. Erythromycin

D. Ciprofloxacin

9531. Heparin, apart from releasing lypoprotein lipase in the blood exerts its anti-coagulant action by____________?
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A. Inhibiting thrombin synthesis

B. Inhibiting prothrombin synthesis

C. Inhibiting fibrinogen synthesis

D. Binding to calcium

9532. Which of the following is correct ?
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A. All of the above

B. Pyknosis shrinkage of nucleus

C. Karyolysis Dissolution of nucleus

D. Karyorrhexis fragmentation of nucleus

9533. Which of the following statement is _____________?
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A. High density lipoproteins have protective role in atherosclerosis

B. Poly unsaturated fats lowers plasma cholesterol levels

C. Low density lipoproteins has maximum association with atherosclerosis

D. HDL contains the highest cholesterol content
9534. Granuloma is characterized by all of the following except______________?
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A. A reaction of acute inflammation

B. A specific type of chronic inflammation

C. Initiated by a number of infectious and non infectious agents

D. Accumulation of modified macrophages

9535. Pale infarcts are seen in all of the following except______________?
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A. Spleen

B. Lung

C. Liver

D. Kidney

9536. The most common site of metastases of osteosarcoma is_____________?
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A. Spleen

B. Lymph nodes

C. Lung

D. Liver

9537. The most common site of origin for venous thrombi leading to pulmonary embolism is_____________?
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A. Deep leg veins

B. Portal vein

C. Ascending oaorta

D. Right atrium

9538. The predominant cells after 48 hours of inflammation are_____________?
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A. A and B

B. Neutrophils

C. Macrophage

D. Monocytes

9539. Virchow Lepra cells are seen in___________?
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A. lepromatous leprosy

B. Ideterminate leprosy

C. Tuberculoid leprosy

D. Borderline tuberculoid leprosy

9540. IN fanconi anemia there is a_______________?
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A. No increased risk of Sq. cell carcinoma

B. Deficiency of copper

C. Mutation of DNA repair gene

D. Purely nutritional disorder etiology

9541. Synthesis of DNA occurs in Which phase of cellAcycle________________?
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A. Synthesis S phase

B. Gap G2 phase

C. Mitosis M phase

D. Gap G1 phase

9542. Enzymes responsible for suppuration are derived chiefly from_____________?
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A. Monocytes

B. Lymphocytes

C. PMNs

D. Eosinophils

9543. Ascites seen in alcoholic liver cirrhosis result form______________?
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A. Decreased protein production by liver

B. Due to increased portal hypertension

C. Due to obstruction of bile duct

D. All of the above

9544. Regeneration by sprouting of axons takes place in which end of transaction of nerve_____________?
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A. Proximal end

B. Distal end

C. Both A and B

D. None of the above

9545. The intramuscular administration of 0.6 mg of atropine sulphate to a 50 kg adult may produce all of the following effects except_____________?
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A. Mydriasis

B. Decreased Sweating

C. Decreased Salivation

D. Bradycardia
9546. Ghon complex of the lung usually____________?
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A. Progresses to tuberculous pneumonia

B. Undergoes calcification

C. Undergoes cavitation

D. Progresses to military tuberculosis

9547. The antidote for heparin is______________?
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A. Protamine sulphate

B. Potassium sulphate

C. Pryosulphate

D. Penicillinase

9548. Earliest lesion in atherosclerosis is_____________?
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A. None of the above

B. Fatty streak

C. Atheroma

D. Fibrous plaque

9549. Immune response to tumour is mediated by_______________?
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A. Humoral mechanism

B. Natural killer cells

C. All of the above

D. Cytotoxic T lymphocytes

9550. Why fetal cells continue to divide but terminally differentiated adult cells do not divide ?
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A. Absence of CD kinase

B. Proteinase is absent in fetus

C. Phosphatase absent in fetal cells

D. There are many cyclin inhibitors which prevent cell to enter into S phase in adult