pharmacology MCQs – Page 5

Practise focused pharmacology questions with marked answers for exam preparation and subject revision.

pharmacology Mcqs
81. Which of the following is NOT a systemic effect of corticosteroid ?
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A. Increase in total amount of circulatory neutrophils

B. Increase in IL-1

C. Anti-inflammatory effect is increased

D. Inhibit phospholipase A2

82. Hallucinations are seen after ________ anesthesia?
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A. Thiopentone

B. Ketamine

C. Nitrous oxide

D. Tentanyl

83. A patient on 300 mg of aspirin will show all the following except________________?
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A. Irreversible inhibition of cyclooxygenase path way

B. Inhibition of thromboxane TXA2

C. Prolonged bleeding time

D. Inhibition of prostaglandin PGI2

84. Following drug which undergo most of its metabolism presystemically______________?
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A. Paracetamol

B. Propranolol

C. Verapamil

D. Salbutamol

85. The dose of a drug required to produce a specified effect in 50% of the population is_____________?
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A. Td50

B. Md50

C. Ed50

D. Ld50

86. Km value indicates______________?
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A. Affinity

B. Purity of Enzyme

C. Physiological role

D. Half life enzymes drug complex
87. Which of the following statements regarding nitroglycerin is true ?
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A. Poorly suited for oral administration

B. High membrane penetrability

C. All of the above

D. The effect is more pronounced in venous

88. About heparin true is_____________?
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A. Decrease action of prothrombin III

B. Half-life is 90 min

C. Known to cause idiopathic thrombocytosis

D. Mixture of sulphated polypeptide

89. Sildenafil is inhibitor of_______________?
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A. PDE-5

B. cAMP

C. cGMP

D. PGI2

90. Mandibular sublaxation is associated with________________?
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A. Ciprofloxacin

B. Prochlorperazine

C. Diphenhydramine

D. Carbamezapine

91. Gastric secretion has been shown to be most effectively reduced with the use of___________?
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A. Adrenal steroids

B. H1 histamine receptor antagonist

C. Anticholinergic

D. H2 histamine receptor antagonist
92. Adrenaline can be given in all of the following situations except_______________?
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A. Shock

B. Myocardial infarction

C. Anaphylaxis

D. Asthma

93. When a drug creates an effect that is unpredictable and unique it is termed as____________?
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A. Idiosyncratic effect

B. Toxicity effect

C. Drug on Drug effect

D. Side effect

94. Nitrous oxide is carried in the blood stream by_____________?
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A. Red Blood cells

B. White blood cells

C. Serum

D. Haemoglobin

95. Drugs showing zero order kinetics of elimination_____________?
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A. Are more common than first order kinetics

B. Show a plot of drug concentration versus time that is linear

C. Have a half life independent of dose

D. Decrease in concentration exponentially with time

96. Rapid onset of inhalational GA depends on____________?
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A. All of the above

B. Cerebral blood flow

C. Partial pressure of GA

D. Blood solubility

97. Loading dose depends on_____________?
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A. Volume of distribution

B. Half life

C. Clearance

D. Rate of administration

98. All of the following are tocolytic except_______________?
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A. Atosiban

B. Ritodrine

C. Natrexam

D. Isoxsuprine

99. Which of the following is not a contraindication in the therapy with opioids_____________?
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A. Use in severe constant pain

B. Use in head injury patient

C. Use of agonist with mixed agonist-antagonist

D. use in impaired pulmonary function

100. Drug injury may be caused by therapeutic drugs or______________?
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A. Carcinogens

B. Nontherapeutic agents

C. All of the above

D. Allergens