microbiology Mcqs
151. The small nonparticulate protein leading to enhanced replication of HBV as well as HIV is______________?
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A. Hbe Ag

B. HBx Ag

C. HBs Ag

D. HBc Ag

152. Which worm is longest________________?
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A. Hook worm

B. T. Saginata

C. A. Lumbricoides

D. T. Solium

153. Kolmer test is a screening test done for_________________?
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A. Tuberculosis

B. Syphilis

C. Lymphoma

D. Gonorrhea

154. Negative phase is seen in ________ immunity?
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A. Local

B. Herd

C. Passive

D. Active
155. Opsonisation is by_______________?
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A. IgA

B. IgE

C. IgG

D. IgM

E. Both C & D
156. Hepatitis A virus is best diagnosed by______________?
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A. IgM antibodies in serum

B. Culture from blood

C. Isolation from bile

D. Isolation form stool

157. Complement binding immunoglobin via the classical pathway is_______________?
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A. IgD & IgE

B. IgG & IgA

C. IgG & igM

D. IgG & IgD

158. Seroconversion in HIV infection takes place in______________?
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A. 4 weeks

B. 12 weeks

C. 9 weeks

D. 2 weeks

159. Same or closely related antigens present in different biological species are known as________________?
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A. Isoantigens

B. Haptens

C. Heterophile antigens

D. Suquestrated antigens

160. Oil and Grease are sterilized by________________?
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A. Auto claving

B. Hot air oven

C. Ethylene dioxide

D. Irradiation

161. What is the sequence which a retro virus follows on entering a host cell ?
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A. DNA-RNA

B. DNA-RNA-DNA

C. RNA -DNA-RNA

D. RNA-DNA

162. A person working in an abattoir presented with a papule on hand, which turned in to an ulcer. Which will best help in diagnosis______________?
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A. Trichrome Methylene blue

B. Carbol Fuschin

C. Calcoflour White

D. Acid Fast Stain

163. Enterically transmitted NANB hepatitis B_____________?
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A. Hepatitis F

B. Hepatitis C

C. Hepatitis D

D. Hepatitis E
164. The virus which causes Aplastic anemia in chronic hemolytic disease is_______________?
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A. EB virus

B. Parvo virus

C. Adeno

D. Hepatitis

165. Which of the following is true about pasteurization ?
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A. It kills bacteria and spores

B. Tubercle bacilli are destroyed

C. It kills all bacteria except thermoduric bacteria

D. It kills 95% of microorganisms

166. Zero growth rate is observed during one of the phase of the bacterial growth curve______________?
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A. Lag

B. Exponential growth

C. Stationary phase

D. Decline

167. Killer and Helper cells are part of_______________?
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A. Macrophage

B. B cells

C. T cells

D. Monocytes

168. The antigen used in Weil Felix test is obtained from________________?
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A. coli

B. Pseudomonas

C. Proteus

D. Staphylococcus

169. Following is a retrovirus_____________?
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A. Influenza

B. Immunodeficiency virus

C. Polio virus

D. Hepatitis virus

170. The medium of choice for growing most fungi is_______________?
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A. Tissue culture

B. Thioglycollate medium

C. Blood agar

D. Sabourauds agar
171. Which of the following is a RNA virus ?
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A. Adeno virus

B. Herpes Virus

C. Papavo virus

D. Measles virus
172. Kaposis sarcoma (KS) usually occurs when CD4 Lymphocyte counts are_____________?
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A. Between 1000-2000

B. Above 2000

C. Below 200

D. Above 600

173. In HIV, gp 120, envelope glycoproteins bind specifically to______________?
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A. NK cells

B. B cells

C. CD4 T-cells

D. CD8 T-cells

174. Tyndallisation is carried out for________________?
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A. Two successive days

B. Three successive days

C. 60 minutes

D. One day

175. During the Window period of patient with AIDS_______________?
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A. ELISA IS ve

B. Western Blot is ve

C. Both are ve

D. PCR is ve

176. Amoebic liver abscess can be diagnosed by demonstratig________________?
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A. Trophozoites in the pus

B. Cysts in the sterile pus

C. Trophozoites in the feces

D. Cysts in the intestine

177. Most common tumor associated with AIDS is______________?
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A. Carcinoma

B. Ewings sarcoma

C. Kaposis sarcoma

D. Melanoma

178. Rabies virus________________?
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A. Neurotropic

B. Chromophilic

C. Cytotropic

D. Dermatotropic

179. Investigation of choice for invasive amoebiasis is________________?
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A. Counter immune electroporesis

B. Microscopy

C. ELISA

D. Indirect hemagglutination

180. Probiotic organism used_________________?
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A. Salmonella

B. Bifido bacteria

C. Staphylococcus

D. E coli

181. Flash pasteurization of milk is done at what temperature______________?
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A. 72 for 15 20 Sec

B. 60C for 15 minutes

C. 125C for new seconds

D. 72C for 5 minutes

182. Which of the following methods is adopted for screening HIV infection ?
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A. ELISA followed by western blot technique

B. Virus isolation

C. Polymers chain reaction

D. Western blot followed by ELISA

183. The anaphylaxis should be treated first with_____________?
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A. Epinephrine

B. Anti histamines

C. Antibiotics

D. Steroids

184. The following is not true of Candida albicans______________?
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A. Blastomeres seen in isolates

B. Seen in immunocompromised and causes meningitis in them

C. Yeast like fungus

D. Forms Chlamydospores

185. Which of the following does not go into chronic hepatitis stage ?
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A. HCV

B. HBV

C. HEV

D. HDV

186. Which of the following is not used as disinfectant________________?
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A. 1-2% cetrimide

B. 2% Lysol

C. 100% alcohol

D. 5% chloroxylene

187. The overall effect of HIV is to gradually impair the immune system by interference with______________?
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A. Plasma cells

B. Macrophages

C. Helper T lymphocytes

D. Natural killer cells

188. Toxoids are_________________?
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A. non-antigenic and toxic

B. non-antigenic and non-toxic

C. antigenic and non-toxic

D. antigenic and toxic

189. The time gap between appearance of Kopliks spot and cutaneous rash in measles is________________?
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A. 24 Hrs

B. 3-4 days

C. 10 days

D. 2 weeks

190. Characteristic feature of retrovirus is_____________?
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A. Restriction endonuclease

B. DNA polymerase

C. Ribonuclease

D. Reverse transcriptase
191. Hepatitis C virus belongs to which one of the following virus groups ?
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A. Flavi viruses

B. Picorna viruses

C. Herpes viruses

D. Hepadana viruses

192. In patients with asthma due to an allergic cause the serum levels of which immunoglobulin increase____________________?
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A. IgE

B. IgD

C. IgM

D. IgA

193. In penicillin allergy, penicillin acts as a_______________?
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A. Carrier

B. Super antigen

C. Toxin

D. Hapten
194. Human immunoglobulins are divided based on_____________?
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A. Structural differences

B. Complemented fixation

C. Functional differences

D. None of the above

195. EBV causes all except_________________?
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A. Papilloma

B. Infectious mononucleosis

C. Carcinoma of nasopharynx

D. Burkitts lymphoma

196. Cold sterilization refers to the process of sterilization by use of____________________?
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A. Infrared rays

B. Gamma rays

C. Ultrasonic vibrations

D. Ultra violet rays

197. Anaphylaxis refers to the________________?
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A. Severe reaction resulting from sensitivity to common allergens

B. Severe reaction following primary injection of Protein solutions

C. Severe reaction following the injection of protein solution in a sensitized individual

D. State of immunity developed by repeated injections of any foreign substance

198. Chemotactic cytokine is_________________?
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A. IL-8

B. TNF

C. IL-6

D. IL-1

199. Viron is defined as______________?
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A. A smallest particle similar to virus

B. Extracellular infectious virus particle

C. Smallest virus

D. None of the above

200. Components of innate immunity that are active against viral cells includes______________?
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A. NK Cells

B. Cytotoxic T cells

C. B cells

D. Memory B cells