microbiology Mcqs
251. A woman with infertility receives an ovary transplant from her sister who is an identical Twin. What type of graft it is ?
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A. Isograft

B. Allograft

C. Xenograft

D. Autograft

252. Portal of entry of poliovirus in mainly_______________?
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A. Nasal mucosa

B. Gastrointestinal tract

C. Lung

D. Skin

253. Most sensitive test for antigen detection is_______________?
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A. ELISA

B. Passive hemaglutination

C. Immunoflourescence

D. Radioimmuno Assay
254. Viruses can be isolated from clinical samples by cultivation in the following except_______________?
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A. Chemically defined media

B. Animals

C. Embryonated eggs

D. Tissue culture

255. All of the following infections may be transmitted be dental instruments except____________?
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A. HIV

B. Hepatitis E

C. Hepatitis B

D. Hepatitis C

256. Following are the characteristics of Cryptococcus neoformans EXCEPT________________?
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A. Basidiomycetes yeast

B. Melanin production related to virulence

C. Causes meningitis

D. Noncapsulated fungus infecting man
257. Which of the following correctly indicates the infectivity of hepatitis virus in human ?
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A. HBeAg

B. Anti-HBS

C. Anti-HBC

D. HBCAg

258. All are oncogenic except________________?
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A. EB virus

B. Varicella zoster virus

C. Papilloma virus

D. Herpes simplex virus
259. Phase contrast microscopy is based on principle of__________________?
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A. Different refractive indices of object

B. Light attenuation

C. Light scattering

D. Different reflective indices of object

260. Virus is cultured in_______________?
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A. Nonembryonated egg

B. Saubourds agar

C. Embryonated egg

D. Rogosa medium

261. One virus particle prevents multiplication of 2nd virus. This phenomena is____________?
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A. Permutation

B. Supervision

C. Mutation

D. Viral interference
262. The following statement is true regarding fungal infection__________________?
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A. Rhinosporidium causes deep infection in man

B. Dermatophyte infection are exclusively man to animal

C. Candida infection is usually endogenous

D. albicans is not pathogenic to lab animals

263. DNA covering material in a virus is called as________________?
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A. Capsomere

B. Capsid

C. Nucleocapsid

D. Envelope

264. The Process of attenuation can be achieved by all except___________________?
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A. Growing bacteria in adverse environment

B. Growing bacteria in unconventional host

C. Serial passage in an experimental host

D. Repeated cultures in artificial media

265. Dengue Hemorrhagic fever is caused by_____________?
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A. Bacteria

B. Parasite

C. Virus

D. Bacteria superadded on virus

266. Most of the drug resistances occurs due to_____________?
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A. Transformation

B. Transduction

C. conjugation

D. Mutation

267. The world german measles is applied for_____________?
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A. Herpes simplex

B. Herpetic ginglvostomatitis

C. Rubeola

D. Rubella
268. Rapid evaluation of fungal hyphae/spores can be achieved with_______________?
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A. KOH wet mount

B. Grocott Gomori Methenamine silver

C. Peri-iodic Acid Schiff

D. Hematoxylin and Eosin

269. Moist heat kills all of the following EXCEPT_______________?
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A. Coxiella burnetti

B. Mycobacterium

C. Brucella

D. Salmonella

270. Group A carbohydrate of Str. pyogenes cross reacts with human_________________?
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A. Cardiac valves

B. Vascular intima

C. Synovial fluid

D. Myocardium

271. All are true about widel test except________________________?
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A. H antigen cannot differentiate between subtypes

B. High titre value in a single widal test is not confirmative

C. O antibodiest last longer and hence is not indicative of recent infection

D. Base lines differ depending on the endemicity of the disease

272. A 6 year old boy comes with abdominal pain, vomiting after consuming mild products within 6 hours. The most likely organism responsible is______________?
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A. B.Cereus

B. Salmonella

C. Clostridium botulinum

D. Staph. aureus
273. Growth factor needed for Salmonella_________________?
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A. B-12

B. Citrate

C. Niacin

D. Tryptophan
274. compared with autoclave, use of a dry heat over for sterilization has the following disadvantages______________?
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A. Causes sharp instruments to dull

B. Time-consuming

C. Causes instruments to rust

D. Less effective

275. VDRL is a________________?
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A. Tube agglutination test

B. Latex agglutination test

C. Tube flocculation test

D. Slide flocculation test
276. Anaerobic bacteria grow_______________?
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A. in the presence of oxygen

B. in the presence of nitrogen

C. differential media

D. in the absence of oxygen
277. The commonest method of detection of diptheria carriers is_______________?
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A. Schick test

B. Casonis test

C. Dick test

D. Charles test

278. One of the following is a treponemal test for diagnosis of syphilis_____________?
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A. FTAB

B. Widal test

C. Kahn test

D. Wasserman test

279. cAMP reaction is shown by which streptococci ?
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A. Group A

B. Group D

C. Group C

D. Group B
280. Which of the following organisms are arranged in cubical packets of eight cocci________________?
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A. Aerococcus

B. Sarcina

C. Micrococcus

D. Staphylococcus

281. Which of the following is obligate aerobe ?
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A. Pseudomonas aerogenosa

B. Proteus

C. coli

D. diphtheria

282. Function of T-lymphocyte is/are________________?
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A. Production of interferon

B. Rosette formation

C. Lymphokine production

D. All of the above
283. A full course of immunization agianst. Telanus with 3 doses to Tetanus toxoid, confers immunity for how many years ?
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A. 10

B. 20

C. 15

D. 5

284. An elderly male patient presented with fever, chest pain, and dry cough, sputum culture showed growth on charcoal yeast Extract Medium, theorganism is______________?
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A. Moraxella catarrhalis

B. Legionella

C. H. influenza

D. Burkholderia cepacia

285. The single most important laboratory test for determining the virulence of staphylococci is___________?
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A. Detection of coagulase

B. Mannitol fermentation

C. The catalase test

D. Hemolysis of sheep erythrocytes

286. Which of the following is not a feature of anaphylaxis ?
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A. None of the above

B. Immediate reaction

C. Delayed reaction

D. passive transfer by serum

287. On a stained slide, clostridium tetani has the appearance of a__________________?
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A. Bunch of a

B. Safely pin

C. Chain of beads

D. Drum stick
288. Immunoglobin, Which is produced first by the fetus in response to infection_______________?
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A. IgM

B. IgG

C. IgD

D. IgA

289. Plasmid__________________?
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A. Involved in multidrug resistance transfer

B. Involved in conjugation

C. Imparts capsule formation

D. Imparts pili formation

E. Both A & B
290. Diphtheria is pathogenic only when infected with______________?
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A. Beta phage

B. Alfa phage

C. Lambda K12

D. Delta Phage

291. The function of IgD is______________?
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A. Antigen recognition by B cells

B. Reagin activity

C. Localization protection in external secretion

D. Compliment activation

292. Which organism causes prosthetic valve endocarditis within 60 days of surgery________________?
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A. Fungus

B. Staphylococcus aureus

C. Streptococcus Viridans

D. Staphylococcus epidermis
293. About Bacteroids True are all Except_______________?
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A. Most common species is B fragilis

B. Bile resistant anerobes

C. Present mainly in mixed infections

D. Susceptible to many antibiotics
294. The diagnosis of gonorrhea is established by_____________?
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A. Pili agglutination tests

B. Haemagglutination tests

C. All of the above tests

D. Compliment fixation tests

295. An example of naturally acquired passive immunity is__________________?
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A. Placental transfer of antibodies

B. Gamma globulin injection

C. Immune blood transfusion

D. Hepatitis vaccination

296. Selective media for MYCOBACTERIUM _____________?
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A. Lowenstein Jensen medium

B. Sabourauds medium

C. Loefflers serum slope

D. Agar agar

297. Encapsulation in bacteria helps in__________________?
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A. Oxygen effect

B. Spore formation

C. Decreased virulence

D. Prevent their phagocytosis
298. Sterilisation is______________?
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A. Non-pathogenic killed

B. All pathogenic and non-pathogenic microorganisms killed

C. Pathogens killed but spores are not affected

D. Only pathogenic micro-organisms killed

299. Dental Plaque adheres to tooth surface by________________?
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A. Bacteria

B. Dextran

C. Epithelial cells

D. Sucrose

300. The interaction of antigens with antibodies on the surface of a mast cel leads to degranulation and anaphylaxis. The mast cell granules produce anaphylaxis because they contain________________?
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A. Proteolytic enzymes

B. Lymphotoxins

C. Vasoactive mediators

D. Lysosomes