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microbiology MCQs

Practise focused microbiology questions with marked answers for exam preparation and subject revision.

microbiology Mcqs

1. The Window period in HIV infection means______________?
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A. The time lapse between obtaining the sample and detection of virus in the lab

B. The time lapse between the infection and development of AIDS

C. The time lapse between the infection and detection of viral antibodies

D. None of the above

2. Human immune deficiency virus is ________________ virus?
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A. Retro

B. Rheo

C. Rhabdo

D. Flavi

3. The classic opportunistic infection in acquired immune deficiency syndrome is_____________?
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A. Tuberculosis

B. Apthous stomatitis

C. Herpetic gingivostomatitis

D. Pneumocystis carinii pneumonia

4. Most common opportunistic infection in AIDS is_____________?
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A. Aspergilosis

B. Cryptococcosis

C. Candidiasis

D. Tuberculosis

5. Cytopathic effect is shown by_____________?
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A. Anaerobe

B. Bacteria

C. Spirochete

D. Virus

6. Viruses can be cultured in all except_______________?
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A. Guinea pigs

B. Blood agar

C. Chick embryo

D. Cell culture

7. Incubation pariod of herpes zoster is________________?
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A. 7-14 days

B. 1 months

C. 1-2 years

D. 3-6 months

8. Following hepatitis B infection through blood transfusion disease manifests in_____________?
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A. 6 months

B. 3 months

C. 1 week

D. 6 week

9. Which of the following would you consider to be general properties of viruses______________?
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A. Contain equal proportions of protein, lipo polysaccharide and nucleic acids

B. Contain DNA but no RNA

C. New virus particle arises directly (by division) from preexisting viruses

D. Fall in to the general size range of 200-3000 angstrom unit

10. Human immunodeficiency virus (HIV) affets_______________?
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A. Mast cells

B. Fibroblasts

C. Red blood cells

D. Helper T lymphocytes (CD4)

11. A rise in the anti-HBc immunoglobulin in a patient indicates________________?
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A. Prodromal phase

B. Convalescence

C. Carrier state

D. Acute infection

12. Influenza is caused by_____________?
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A. Paramyxo virus, which is a DNA virus

B. Orthomyxo virus, which is a RNA virus

C. Orthomyxo virus, which is a DNA virus

D. Paramyxo virus, which is a RNA virus

13. True about prions________________?
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A. Phase in which virus cannot be demonstrated in host cell

B. Viral components may be synthesized but maturation & assembling is defective

C. Viruses which are genetically deficient

D. Composed largely proteins without any nucleic acid

14. Both intranuclear and intracytoplasmic inclusions are present in which of the following viruses_____________?
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A. Hepatitis B virus

B. Pox virus

C. HIV

D. Measles virus

15. In which of the following immunization is given after infection is started________________?
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A. Influenza

B. Herpes

C. Rabies

D. Poliomyelitis

16. Herpes virus_____________?
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A. None of the above

B. Acquires its envelope from nucleolar membrane

C. Acquires its envelope from nuclear membrane

D. Acquires its envelope from cytoplasmi membrane

17. Pigs are important source of_____________?
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A. Yellow fever

B. Rabies

C. Japanese encephalitis

D. Kuru

18. Type I hypersensitivity is mediated by which of the following immunoglobulins ?
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A. IgM

B. IgA

C. IgE

D. IgG

19. Antibiotic sensitivity and resistance of micro organisms is determined by________________?
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A. ELISA

B. Culture

C. DNA probe

D. Direct microscopy

20. Man is the only reservoir for_______________?
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A. Salmonella

B. Camphylobacter jejuni

C. histolytica

D. Y. enterocolitica

21. Cysticercosis celluosae is caused by_____________?
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A. T. Solium

B. Echinococcus granulosus

C. T. Saginata

D. nana

22. Hot air oven is used for sterilization of all EXCEPT__________________?
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A. Sharp instrument

B. Glassware

C. Liquid paraffin

D. Rubber tubes

23. Glutaraldehyde is preferred more than formaldehyde because______________?
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A. Its application is easier

B. It has got more bactericidal activity

C. It has got no deleterious effect on the cement and lenses of instruments

D. It has got more bacteriostatic activity

24. Baby born to mother suffering from AIDS, all are true except________________?
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A. Have infections

B. All are true

C. Failure to thrive

D. 50% chances to have AIDS

25. ELISA test when compared to western blot technique is______________?
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A. More sensitive, more specific

B. Less sensitive, more specific

C. More sensitive, less specific

D. Less sensitive less specific

26. Medusa lock appearance in X ray is seen in______________?
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A. Tapeworm

B. Ascariasis

C. Hood worm

D. Ascariasis and tapeworm

27. The prototype of Type II hypersensitivity reaction is__________________?
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A. Auto immune hemolytic anemia

B. SLE

C. Arthus reaction

D. Contact dermatitis

28. Mesophilic organisms are those that grow best at temperature of______________?
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A. 55C to 80C

B. -20C to -7C

C. -7C to + 20C

D. 25C to 40C

29. Which of the following is not transmitted by lice ?
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A. Epidemic typhus

B. Relapsing fever

C. Trench fever

D. Q fever

30. The viral action is differentiated from bacterial action by_________________?
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A. Interferon production

B. Lymphocytes production

C. Toxin production

D. Neutrophils production

31. Type of receptor present on T-cells are__________________?
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A. Ig A

B. CD4

C. Prostaglandins

D. Ig G

32. All are oncogenic except________________?
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A. Anopheles

B. Mansoni

C. Culex

D. Aedes

33. Immunity that is conferred to the foetus by transfer of IgG and IgA antibodies is called as______________?
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A. Passive acquired immunity

B. Passive natural immunity

C. Natural active immunity

D. Active acquired immunity

34. The usual concentration of agar used in agar medium is___________________?
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A. 15%

B. 2%

C. 10%

D. 5%

35. Which of the following statement about P24 antigen of HIV is Not True ?
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A. It can be detected during the window period

B. Free P24 antigen disappears after the appearance of IgM response to it:

C. It remains during asymptomatic phase

D. Virus load parallel P24 titre

36. Which of the following represents the serologic evidence of recent Hepatitis B virus infection during window period ?
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A. HBs Ag

B. IgM anti HBc

C. None of the above

D. Anti HBs

37. Megaloblastic anaemia is caused by_________________?
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A. Threadworm

B. Hookworm

C. Fish tapeworm

D. Dog tapeworm

38. Presence of HBe Ag in patients with hepatitis indicates_____________?
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A. Late convalescence

B. High infectivity

C. Simple carriers

D. Carrier status

39. Post streptococcal acute glomerulo nephritis is an example of________________?
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A. Type III hypersensitivity

B. Type IV hypersensitivity

C. Type I hypersensitivity

D. Type II hypersensitivity

40. The following hepatitis virus is transmitted by faeco-oral route________________?
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A. Hepatitis B virus

B. Hepatitis E virus

C. Hepatitis D virus

D. Hepatitis C virus

41. Which of the following parasite causes autoinfection_________________?
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A. Taenia solium

B. Giardia lambella

C. Balantidium coli

D. Isopora belli

42. Sporozoites of plasmodium falciparum are shaped_______________?
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A. Sickle

B. Dot

C. Comma

D. Banana

43. A dentist suffred from Hepatitis B infection 3 months back. His laboratory tests are normal but he is not allowed by the medical board to do surgical practice. He is_____________?
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A. Paradoxical carrier

B. Inactive carrier

C. Convalscent carrier

D. Healthy carrier

44. Endoscopes are sterilized by using_______________?
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A. Cidex

B. Gamma radiation

C. Autoclaving

D. Boiling

45. A cerebrospinal fluid of a 2 years old child has been sent to the laboratory to detect the presence of capsulated yeast. The staining technique most commonly employed for the purpose is______________?
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A. India ink preparation

B. Ziehl-Neelsen stain

C. Pyte-ferraco stain

D. Methanamine silver stain

46. Rh incompatibility is which type of hyper sensitivity reaction ?
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A. Type I

B. Type III

C. Type IV

D. Type II

47. Active artificial immunization is induced by the administration of all of the following EXCEPT______________?
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A. Vaccines

B. Antitoxins

C. Toxoids

D. Bacterial products

48. patients with organ transplants are most frequently infected with______________?
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A. EBV

B. Hepatitis B

C. CMV

D. Hepatitis A

49. Candida albicans causes all of the following except______________?
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A. Meningitis

B. Endocarditis

C. Oral thrush

D. Mycetoma

50. Best method of sterilizing disposable syringes_______________?
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A. Gamma rays

B. U.V. rays

C. Hot air oven

D. Boiling

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